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Mx2 Antibody (N-17): sc-47197

 |  Datasheet

(Based on data analysis)

  • Mx2 Antibody (N-17) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of Mx2 of human origin
  • recommended for detection of Mx2 of human origin by WB, IP, IF and ELISA
  • blocking peptide, sc-47197 P
 

See additional Mx Antibodies including Mx, Mx1, Mx2 and Mx3.

Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Mx2 Antibody (N-17) sc-47197 200 µg/ml $279
Mx2 (N-17) P sc-47197 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Mx2 siRNA (h) sc-61110 10 µM $258
Mx2 (h)-PR sc-61110-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Mx2 shRNA Plasmid (h) sc-61110-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Mx2 shRNA (h) Lentiviral Particles sc-61110-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Mx2 (h): 293T Lysate sc-114275 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MX2 4600 21q22.3 NM_002463 P20592
147890
 


Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.

Mx2 Antibody (N-17) Data
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Mx2 (N-17): sc-47197. Western blot analysis of Mx2 expression in non-transfected: sc-117752 (A) and human Mx2 transfected: sc-114275 (B) 293T whole cell lysates.
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