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- rabbit polyclonal IgG, 200 µg/ml
- produced by immunization with full length polyhistidine tagged CREM-1 fusion protein of mouse origin
- recommended for detection of CREM-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; partial cross-reactivity with other ATF/CREB proteins and other CREM isoforms; also reactive with additional species, including porcine
- TransCruz reagent for Gel Supershift and ChIP applications, sc-440 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
CREM |
1390 |
10p11.21 |
NM_001881, NM_181571, NM_182717, NM_182718, NM_182719, NM_182720, NM_182721, NM_182722, NM_182723, NM_182724, NM_182725, NM_182769, NM_182770, NM_182771, NM_182772, NM_182850, NM_182853, NM_183011, NM_183012, NM_183013, NM_183060 |
Q03060
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123812 |
| Mouse |
Crem |
12916 |
18 A1 |
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P27699
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N/A |
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CREM-1 Background Information
Eukaryotic gene transcription is regulated by sequence specific transcription factors which bind modular cis acting promoter and enhancer elements. The cAMP response element (CRE), one of the best studied of such elements, consists of the palindromic octanucleotide TGACGTCA. Several CRE binding proteins have been identified within the ATF/CREB family, the best characterized of which include CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. These proteins share highly related COOH terminal leucine zipper dimerization and basic DNA binding domains but are highly divergent in their amino terminal domains. Members of the CREB-related CREM-å and CREM-∫ proteins share a kinase-inducible domain with CREB but act as transcriptional repressors rather than activators.
| CREM-1 (X-12) Product Citations |
See how others have used CREM-1 (X-12): sc-440 antibody and or CREM-1 (X-12) antibody conjugates.
28 total citations Loading citations.
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CREM-1 (X-12)
Click on image to enlarge
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CREM-1 (X-12): sc-440. Western blot analysis of ATF-1/CREB gene family product expression in Jurkat (A) and KNRK (B) nuclear extracts and recombinant mouse His-tagged CREM-1 (FL): sc-4005 (C) and an unrelated His-tagged protein (D). CREM-1 (X-12): sc-440. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing nuclear staining of cells in ductus seminiferus at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
CREM-1 (X-12): sc-440. Western blot analysis of CREM-1 expression in Jurkat nuclear extract.
CREM-1 (X-12): sc-440. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar and nuclear localization.
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