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home »  » c-Jun (D): sc-44

c-Jun (D) Antibody: sc-44

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml; also available as goat IgG, 200 µg/ml, sc-44-G
  • epitope mapping a highly conserved DNA binding domain of c-Jun p39 of mouse origin
  • recommended for detection of c-Jun, Jun B and Jun D p39 proteins of mouse, rat, human, chicken and Xenopus origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine, porcine and avian
  • blocking peptide, sc-44 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-44 X, 200 µg/0.1 ml
 
Additional c-Jun Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human JUN 3725 1p32.1 NM_002228 P05412
 165160
Mouse Jun 16476 4 C5 P05627
 N/A
Mouse Jund 16478 8 B3.3 P15066
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
c-Jun (D) sc-44 200 µg/ml $279
c-Jun (D) P sc-44 P
(peptide)
 100 µg/0.5 ml $61
c-Jun (D) X sc-44 X 200 µg/0.1 ml $279
c-Jun (D)-G sc-44-G 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
c-Jun siRNA (h) sc-29223 10 µM $258
c-Jun siRNA (m) sc-29224 10 µM $258
c-Jun siRNA (h2) sc-44201 10 µM $258
c-Jun (h)-PR sc-29223-PR 10 µM $23
c-Jun (m)-PR sc-29224-PR 10 µM $23
c-Jun (h2)-PR sc-44201-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
c-Jun shRNA Plasmid (h) sc-29223-SH 20 µg $520
c-Jun shRNA Plasmid (m) sc-29224-SH 20 µg $520
c-Jun shRNA Plasmid (h2) sc-44201-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
c-Jun shRNA (h) Lentiviral Particles sc-29223-V 200 µl $625
c-Jun shRNA (m) Lentiviral Particles sc-29224-V 200 µl $625
c-Jun shRNA (h2) Lentiviral Particles sc-44201-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NIH/3T3 + PMA nuclear extract sc-2125 1000 µg $143
Jurkat nuclear extract sc-2132 1000 µg $143

c-Jun Background Information
Genes belonging to the Jun and Fos oncogene families encode nuclear proteins that are associated with a number of transcriptional complexes. The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, while Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. An inhibitor of Fos/Jun function, termed IP-1, associates with Fos and Jun and is inactivated upon phosphorylation induced by the cAMP-dependent protein kinase A (PKA).

c-Jun (D) Product Citations
See how others have used c-Jun (D): sc-44 antibody and or c-Jun (D) antibody conjugates.


124 total citations
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c-Jun (D)
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sc-44
Western blot analysis of c-Jun p39 expression in untreated (A,C) and phorbol ester-induced (B,D) NIH/3T3 nuclear extracts. Antibodies tested include c-Jun (D): sc-44 (A,B) and c-Jun (N): sc-45 (C,D).
sc-44
c-Jun (D): sc-44. Western blot analysis of c-Jun expression in Jurkat nuclear extract.
sc-44
ChiP analysis of transcription factor binding to the CD28 responsive positive regulatory region IV (PRRIV) in resting (A,B) and CD3+CD28-stimulated human primary T cells. 10% (A,C) and 1% (B,D) of input DNAs were amplified. Antibodies used included c-Jun (D): sc-44; c-Fos (6-2H-2F): sc-447 and Ets-1/Ets-2 (C-275): sc-112. Data kindly provided by J. Imbert and reproduced with permission from Yeh, J.H., et al, Mol. Cell. Biol., 2001, 21:4515-4527.
sc-44
c-Jun siRNA (m): sc-29224. Western blot analysis of c-Jun expression in nontransfectedcontrol (A) and c-Jun siRNA transfected (B) NIH/3T3 cells. Blot probed with c-Jun: sc-44. GAPDH (FL-335): sc-25778 used as specificity and loading control.
sc-44
c-Jun (D): sc-44. Western blot analysis of c-Jun expression in non-transfected (A) and human c-Jun transfected (B) CHO whole cell lysates.
sc-44
c-Jun (D): sc-44. Western blot analysis of c-Jun expression in non-transfected: sc-110760 (A) and human c-Jun transfected: sc-110759 (B) 293 whole cell lysates.
sc-44
c-Jun (D): sc-44. Western blot analysis of c-Jun expression in non-transfected: sc-117752 (A) and mouse c-Jun transfected: sc-125069 (B) 293T whole cell lysates.
sc-44
c-Jun (D): sc-44. Western blot analysis of c-Jun expression in non-transfected: sc-117752 (A) and mouse c-Jun transfected: sc-125070 (B) 293T whole cell lysates.
sc-44
c-Jun (D): sc-44. Western blot analysis of c-Jun expression in non-transfected 293T: sc-117752 (A), mouse c-Jun transfected 293T: sc-125071 (B) and NIH/3T3 (C) whole cell lysates.
sc-44
c-Jun (D): sc-44. Western blot analysis of Jun D expression in non-transfected: sc-117752 (A) and mouse Jun D transfected: sc-121171 (B) 293T whole cell lysates and NIH/3T3 nuclear extract (C).
sc-44
c-Jun (D): sc-44. Western blot analysis of c-Jun expression in non-transfected CHO: sc-117750 (A), human c-Jun transfected CHO: sc-110019 (B) and NIH/3T3 (C) whole cell lysates.
sc-44
c-Jun (D): sc-44. Western blot analysis of c-Jun expression in non-transfected 293T: sc-117752 (A), human c-Jun transfected 293T: sc-159456 (B) and UV irradiated HeLa (C) whole cell lysates.
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