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Ubiquitin Aldehyde

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Application:An inhibitor of isopeptidase T and Ubiquitin C-terminal Hydrolase activity
Purity:≥95%
Molecular Weight:8500
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Ubiquitin Aldehyde sc-4316 50 µg $122
Description
Ubiquitin Aldehyde has shown to inhibit the activity of USP5 and UCL-L1. Useful in the stabilization of ubiquitin-protein conjugates in vitro, enhancing their accumulation in cell lysates and tissue extracts. Inhibits deubiquitinylating enzyme activity by this compound can be used to identify such activity to determine the inhibition kinetics for a particular enzyme. A potent, highly specific inhibitor of all ubiquitin deconjugating enzymes, including ubiquitin C-terminal hydrolases (UCHs), ubiquitin-specific proteases (USPs) and deubiquitinylating enzymes (DUBs). Concentration recommended for maximal inhibition is 2-5µM.
Technical Information
Formulation:1mg/ml in water containing 0.15M HCl
Appearance:Aqueous solution
Physical State:Liquid
Solubility:Soluble in aqueous buffers, DMSO (50 mg/ml), and water.
Storage:Store at 4° C
Safety and Reference Information
WGK Germany:3
EC Number:231-791-2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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