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- mouse monoclonal IgG1; 200 µg/ml
- epitope corresponding to amino acids 195-208 mapping within a region of E47 (Pan-1) of human origin that is conserved between E47 and E12 (Pan-2)
- recommended for detection of E47, E12 and ITF-1 of mouse, rat and human origin by WB, IP and IF
- TransCruz reagent for Gel Supershift and ChIP applications, sc-416 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
TCF3 |
6929 |
19p13.3 |
NM_003200 |
P15923
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147141 |
| Mouse |
Tcfe2a |
21423 |
10 C1 |
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P15806
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N/A |
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E2A Background Information
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development include Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and heterooligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.
| E2A (Yae) Product Citations |
See how others have used E2A (Yae): sc-416 antibody and or E2A (Yae) antibody conjugates.
24 total citations Loading citations.
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E2A (Yae)
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E2A (Yae): sc-416. Western blot analysis of E47 expression in Jurkat (A) and K-562 (B) whole cell lysates.
Western blot analysis of human recombinant E47 (A,B,D) and human recombinant E12 (C) fusion proteins. Antibodies tested include E47 (N-649): sc-763 (A), E2A (Yae): sc-416 (B) and E2A.E12 (V-18): sc-349 (C,D). E2A (Yae): sc-416. Western blot analysis of E2A expression in non-transfected 293T: sc-117752 (A), mouse E2A transfected 293T: sc-119880 (B) and Jurkat (C) whole cell lysates. E2A (Yae): sc-416. Western blot analysis of E2A expression in non-transfected 293T: sc-117752 (A), mouse E2A transfected 293T: sc-119881 (B) and Jurkat (C) whole cell lysates. |
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