Molecular structure of Pyoluteorin, CAS Number: 25683-07-2
Pyoluteorin (CAS 25683-07-2)
See product citations (2)
Alternate Names:
(4,5-dichloro-1H-pyrrol-2-yl)-(2,6-dihydroxyphenyl)methanone
Application:
Pyoluteorin is a small chlorinated pyrrol with a broad bioprofile
CAS Number:
25683-07-2
Purity:
≥98%
Molecular Weight:
272.08
Molecular Formula:
C11H7Cl2NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Pyoluteorin is a small chlorinated pyrrol produced by several species of Pseudomonas, first reported in 1958. Pyoluteorin exhibits a broad bioprofile, demonstrating antibiotic, antifungal and herbicidal activity. More recently, pyoluteorin has been investigated as bio-pesticide and may act to modulate the levels of metabolites in Pseudomonas.
Pyoluteorin (CAS 25683-07-2) References
- Positive autoregulation and signaling properties of pyoluteorin, an antibiotic produced by the biological control organism Pseudomonas fluorescens Pf-5. | Brodhagen, M., et al. 2004. Appl Environ Microbiol. 70: 1758-66. PMID: 15006802
- Reciprocal regulation of pyoluteorin production with membrane transporter gene expression in Pseudomonas fluorescens Pf-5. | Brodhagen, M., et al. 2005. Appl Environ Microbiol. 71: 6900-9. PMID: 16269724
- Phloroglucinol mediates cross-talk between the pyoluteorin and 2,4-diacetylphloroglucinol biosynthetic pathways in Pseudomonas fluorescens Pf-5. | Kidarsa, TA., et al. 2011. Mol Microbiol. 81: 395-414. PMID: 21564338
- Pyoluteorin derivatives induce Mcl-1 degradation and apoptosis in hematological cancer cells. | Doi, K., et al. 2014. Cancer Biol Ther. 15: 1688-99. PMID: 25535900
- Detection of antimicrobial traits in fluorescent pseudomonads and molecular characterization of an antibiotic pyoluteorin. | Vinay, JU., et al. 2016. 3 Biotech. 6: 227. PMID: 28330299
- Mindapyrroles A-C, Pyoluteorin Analogues from a Shipworm-Associated Bacterium. | Lacerna, NM., et al. 2019. J Nat Prod. 82: 1024-1028. PMID: 30793902
- Pyoluteorin induces cell cycle arrest and apoptosis in human triple-negative breast cancer cells MDA-MB-231. | Ding, T., et al. 2020. J Pharm Pharmacol. 72: 969-978. PMID: 32246778
- Pyoluteorin Induces Apoptosis and Autophagy in NSCLC Cells. | Fan, D., et al. 2021. Biol Pharm Bull. 44: 976-983. PMID: 34193693
- Two Pathway-Specific Transcriptional Regulators, PltR and PltZ, Coordinate Autoinduction of Pyoluteorin in Pseudomonas protegens Pf-5. | Yan, Q., et al. 2021. Microorganisms. 9: PMID: 34361923
- The Lon protease negatively regulates pyoluteorin biosynthesis through the Gac/Rsm-RsmE cascade and directly degrades the transcriptional activator PltR in Pseudomonas protegens H78. | Wang, Z., et al. 2022. Environ Microbiol Rep. 14: 506-519. PMID: 35297175
- Pyoluteorin Produced by the Biocontrol Agent Pseudomonas protegens Is Involved in the Inhibition of Heterobasidion Species Present in Europe. | Pellicciaro, M., et al. 2022. Pathogens. 11: PMID: 35456066
- The Role of Pyoluteorin from Pseudomonas protegens Pf-5 in Suppressing the Growth and Pathogenicity of Pantoea ananatis on Maize. | Gu, Q., et al. 2022. Int J Mol Sci. 23: PMID: 35742879
- Pyoluteorin and 2,4-diacetylphloroglucinol are major contributors to Pseudomonas protegens Pf-5 biocontrol against Botrytis cinerea in cannabis. | Balthazar, C., et al. 2022. Front Microbiol. 13: 945498. PMID: 36016777
- Regulatory roles of RpoS in the biosynthesis of antibiotics 2,4-diacetyphloroglucinol and pyoluteorin of Pseudomonas protegens FD6. | Zhang, QX., et al. 2022. Front Microbiol. 13: 993732. PMID: 36583049
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pyoluteorin, 1 mg | sc-391693 | 1 mg | $296.00 | |||
Pyoluteorin, 5 mg | sc-391693A | 5 mg | $807.00 |