DHCR24 Antibody (D-10): sc-390037
- DHCR24 Antibody (D-10) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of DHCR24 of human origin
- recommended for detection of DHCR24 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DHCR24 Antibody (D-10) for WB and IHC(P) applications. These reagents are now offered in bundles with DHCR24 Antibody (D-10) (see ordering information below).
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DHCR24 Antibody (D-10) is a mouse monoclonal IgG1 antibody that detects DHCR24 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). DHCR24, also known as 3-β-hydroxysterol Delta-24 reductase or seladin-1, plays a crucial role in cholesterol biosynthesis by catalyzing the reduction of the Delta-24 double bond in sterol intermediates, which is essential for maintaining cellular cholesterol homeostasis. DHCR24 is predominantly expressed in the adrenal gland and brain, where DHCR24 is localized to the endoplasmic reticulum and Golgi apparatus, highlighting DHCR24′s importance in steroidogenesis and neurosteroid production. Defects in the DHCR24 gene can lead to desmosterolosis, an autosomal recessive disorder characterized by abnormal cholesterol metabolism, underscoring the significance of DHCR24 in human health. Anti-DHCR24 antibody (D-10) is an invaluable tool for researchers studying cholesterol metabolism and related disorders, providing reliable detection and characterization of this critical protein.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DHCR24 Antibody (D-10) | sc-390037 | 200 µg/ml | $316.00 | |||
DHCR24 Antibody (D-10): m-IgG Fc BP-HRP Bundle | sc-538056 | 200 µg Ab; 10 µg BP | $354.00 | |||
DHCR24 Antibody (D-10): m-IgGκ BP-HRP Bundle | sc-535583 | 200 µg Ab; 40 µg BP | $354.00 | |||
DHCR24 Antibody (D-10): m-IgG1 BP-HRP Bundle | sc-545503 | 200 µg Ab; 20 µg BP | $354.00 |