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GP-39 Antibody (E-11): sc-376910

 |  Datasheet

(Based on data analysis)

  • GP-39 Antibody (E-11) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against amino acids 136-178 mapping within an internal region of GP-39 of mouse origin
  • recommended for detection of GP-39 of mouse origin by WB, IP, IF and ELISA
 
Full-length GP-39 protein sequence with immunogen highlighted:
MHTSTEARMGMRAALTGFAVLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFANISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGEKRFSEIASNTERRTAFVRSVAPFLRSYGFDGLDLAWLYPRLRDKQYFSTLIKELNAEFTKEVQPGREKLLLSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQITGHHSPLFQGQKDTRFDRYSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLASSENQLGAPISGEGLPGRFTKEAGTLAYYEICDFLKGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVGFLKEKKLAGAMVWALDLDDFQGTCQPKEFFPLTNAIKDALA

See additional GP-39 Antibodies.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
GP-39 Antibody (E-11) sc-376910 200 µg/ml $279
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Chi3l1 12654 1 E4 NM_007695 Q61362
N/A
 


Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.

GP-39 Antibody (E-11) Data
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GP-39 (E-11): sc-376910. Western blot analysis of GP-39 expression in non-transfected: sc-117752 (A) and mouse GP-39 transfected: sc-120569 (B) 293T whole cell lysates.
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