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β-catenin Antibody (B-9): sc-376841

 |  Datasheet

(Based on data analysis)

  • β-catenin Antibody (B-9) is a mouse monoclonal IgG3 provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 755-781 at the C-terminus of β-catenin of human origin
  • recommended for detection of β-catenin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
 

See additional Catenin Antibodies including Catenin, alpha E-catenin, alpha N-catenin, alpha T-catenin , beta-catenin, delta-catenin and gamma-catenin.

Also see beta-catenin Inhibitors for functional analysis of cellular responses to beta-catenin.


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β-catenin Antibody (B-9) sc-376841 200 µg/ml $279


The catenins, å, ∫ and ©, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. å-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. ∫-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. ∫-catenin has also been found in complexes with the tumor suppressor protein APC. ©-catenin, also known as plakoglobin, binds with å-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTPµ associates with catenin/cadherin complexes and may regulate complex signaling.

β-catenin Antibody (B-9) Data
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β-catenin (B-9): sc-376841. Western blot analysis of β-catenin expression in non-transfected: sc-117752 (A) and human β-catenin transfected: sc-116622 (B) 293T whole cell lysates.
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