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HIRIP3 Antibody (D-10): sc-376814

 |  Datasheet

(Based on data analysis)

  • HIRIP3 Antibody (D-10) is a mouse monoclonal IgG2a provided at 200 µg/ml
  • raised against amino acids 1-100 mapping at the N-terminus of HIRIP3 of human origin
  • recommended for detection of HIRIP3 of human origin by WB, IP, IF and ELISA
 
Full-length HIRIP3 protein sequence with immunogen highlighted:
MAREKEMQEFTRSFFRGRPDLSTLTHSIVRRRYLAHSGRSHLEPEEKQALKRLVEEELLKMQVDEAASREDKLDLTKKGKRPPTPCSDPERKRFRFNSEESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSPEAKGGKAGSGRRGEDHPAVMRLKRYIRACGAHRNYKKLLGSCCSHKERLSILRAELEALGMKGTPSLGKCRALKEQREEAAEVASLDVANIISGSGRPRRRTAWNPLGEAAPPGELYRRTLDSDEERPRPAPPDWSHMRGIISSDGESN

See additional HIRIP Antibodies.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
HIRIP3 Antibody (D-10) sc-376814 200 µg/ml $279
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human HIRIP3 8479 16p11.2 NM_003609 Q9BW71
 603365
 

The HIRIP3 (HIRA interacting protein 3) locus encodes for a 556 amino acid protein that directly interacts with the HIRA histone chaperone. It also interacts weakly with core histones, Histone H2B and Histone H3. HIRIP3 is a heavily phosphorylated nuclear protein and it is found throughout the cell cycle. It is phosphorylated by casein kinase II. HIRIP3 may play a role in chromatin function and histone metabolism. A region (approximately 60 amino acids in length) at the C-terminus of HIRIP3 is highly conserved among vertebrates and it contains residues that are invariantly charged, polar, and hydrophobic. Two isoforms of HIRIP3 exists due to alternative splicing. Isoform 1 is predominately expressed in skeletal muscles and isoform 2 is expressed in the liver and the heart. Human HIRA homologs are thought to be responsible for the DiGeorge syndrome and related developmental disorders.

HIRIP3 Antibody (D-10) Data
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sc-376814
HIRIP3 (D-10): sc-376814. Western blot analysis of HIRIP3 expression in Jurkat nuclear extract.
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