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PI 3-kinase p85α Antibody (C-1): sc-376112

 |  Datasheet

(Based on data analysis)

  • PI 3-kinase p85α Antibody (C-1) is a mouse monoclonal IgG2b provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 7-43 near the N-terminus of PI 3-kinase p85α of human origin
  • recommended for detection of PI 3-kinase p85α of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, bovine and avian
  • See 1 citations for PI 3-kinase p85α Antibody (C-1)
 

See additional PI 3-kinase Antibodies including PI 3-kinase, PI 3-kinase C2 alpha, PI 3-kinase C2 beta, PI 3-kinase C2 gamma, PI 3-kinase p55 gamma, PI 3-kinase p85 alpha, PI 3-kinase p85 beta, PI 3-kinase p100, PI 3-kinase p101, PI 3-kinase p110, PI 3-kinase p110 alpha, PI 3-kinase p110 beta, PI 3-kinase p110 delta and PI 3-kinase p110 gamma.

Also see PI 3-kinase p85 alpha Inhibitors for functional analysis of cellular responses to PI 3-kinase p85 alpha.


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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
PI 3-kinase p85α Antibody (C-1) sc-376112 200 µg/ml $279
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PIK3R1 5295 5q13.1 NM_001242466, NM_181504, NM_181523, NM_181524 P27986
 171833
Mouse Pik3r1 18708 13 D1 NM_001024955, NM_001077495 P26450
 N/A
 

Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of (p85) and (p110) subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85å and p85∫), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110å and p110∫ interact with p85å, and p110å has also been shown to interact with p85∫ in vitro. p110∂ expression is restricted to white blood cells. It has been shown to bind p85å and ∫, but it apparently does not phosphorylate these subunits. p110∂ seems to have the capacity to autophosphorylate. p110© does not interact with the p85 subunits. It has been shown to be activated by å and ∫© heterotrimeric G proteins.

PI 3-kinase p85α Antibody (C-1) Product Citations
See how others have used PI 3-kinase p85α Antibody (C-1) and or PI 3-kinase p85α Antibody (C-1) conjugates.


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PI 3-kinase p85α Antibody (C-1) Data
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sc-376112
PI 3-kinase p85α (C-1): sc-376112. Western blot analysis of PI 3-kinase p85α expression in non-transfected: sc-117752 (A) and mouse PI 3-kinase p85α transfected: sc-122557 (B) 293T whole cell lysates.
sc-376112
PI 3-kinase p85α (C-1): sc-376112. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing cells in germinal and non-germinal centers.
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