Troponin I-FS Antibody (E-2): sc-374549

Troponin I-FS Antibody (E-2) is a mouse monoclonal IgG3 antibody that detects Troponin I in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Troponin I plays a critical role in muscle contraction by regulating the interaction between actin and myosin, which is essential for muscle function and overall movement. Troponin I is part of the troponin complex, which also includes Troponin C and Troponin T, and is specifically responsible for inhibiting actin-myosin interactions in the absence of calcium. When calcium binds to Troponin C, a conformational change allows Troponin I to release its inhibitory grip on actin, thereby facilitating muscle contraction. Precise regulation of Troponin I is vital for proper muscle function, as alterations in expression or function can lead to various cardiac and skeletal muscle disorders. Anti-Troponin I antibody (E-2) serves as an invaluable tool for researchers studying muscle physiology and pathophysiology, providing insights into the mechanisms of muscle contraction and the role of troponin in health and disease.

The preferred Troponin I-FS antibody is Troponin I-FS Antibody (C-11): sc-377451.