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cathepsin D Antibody (F-12): sc-374381

 |  Datasheet

(Based on data analysis)

  • cathepsin D Antibody (F-12) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 69-97 at the N-terminus of cathepsin D of human origin
  • recommended for detection of cathepsin D of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including porcine
 

See additional Cathepsin Antibodies including Cathepsin, cathepsin 1, cathepsin 3, cathepsin 8, cathepsin A, cathepsin B, cathepsin C, cathepsin D, cathepsin E, cathepsin F, cathepsin G, cathepsin H, cathepsin J, cathepsin K, cathepsin L, cathepsin M, cathepsin O, cathepsin Q, cathepsin R, cathepsin S, cathepsin V, cathepsin W, cathepsin Z, pan cathepsin and cathepsin 6.

Also see cathepsin D Inhibitors for functional analysis of cellular responses to cathepsin D.


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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
cathepsin D Antibody (F-12) sc-374381 200 µg/ml $279
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CTSD 1509 11p15.5 NM_001909 P07339
 610127
Mouse Ctsd 13033 7 F5 NM_009983 P18242
 N/A
 

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.
cathepsin D Antibody (F-12) Data
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sc-374381
cathepsin D (F-12): sc-374381. Western blot analysis of cathepsin D expression in MCF7 (A) and ZR-75-1 (B) whole cell lysates.
sc-374381
cathepsin D (F-12): sc-374381. Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing cytoplasmic staining of glandular cells.
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