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Fibrillarin Antibody (G-8): sc-374022

 |  Datasheet

(Based on data analysis)

  • Fibrillarin Antibody (G-8) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 99-127 within an internal region of Fibrillarin of human origin
  • recommended for detection of Fibrillarin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine, bovine and porcine
 

See additional Fibrillarin Antibodies.

Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   IHC(P)   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Fibrillarin Antibody (G-8) sc-374022 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fibrillarin siRNA (h) sc-37883 10 µM $258
Fibrillarin siRNA (m) sc-37884 10 µM $258
Fibrillarin (h)-PR sc-37883-PR 10 µM, 20 µl $23
Fibrillarin (m)-PR sc-37884-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fibrillarin shRNA Plasmid (h) sc-37883-SH 20 µg $520
Fibrillarin shRNA Plasmid (m) sc-37884-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fibrillarin shRNA (h) Lentiviral Particles sc-37883-V 200 µl $625
Fibrillarin shRNA (m) Lentiviral Particles sc-37884-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human FBL 2091 19q13.31 NM_001436 P22087
134795
Mouse Fbl 14113 7 A3 NM_007991 P35550
N/A
 


Fibrillarin is a widely occurring, basic, nonhistone protein that is localized exclusively in the fibrillar region of the nucleolus, including both the dense fibrillar and the fibrillar center regions. Fibrillarin is a protein that is also expressed in HeLa cells, 3T3 cells, and human peripheral blood lymphocytes. In metaphase and anaphase, fibrillarin is found on putative chromosomal nucleolar regions (NORs). During telophase, fibrillarin is an early marker for the site of the newly forming nucleolus. The structure of fibrillarin includes an RNA-binding domain and an RNP consensus sequence, which is consistent with the association of fibrillarin with the U3 small nucleolar RNA. Fibrillarin is involved in processing rRNA transcripts in the nucleolus.

Fibrillarin Antibody (G-8) Data
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Fibrillarin (G-8): sc-374022. Western blot analysis of Fibrillarin expression in non-transfected: sc-117752 (A) and mouse Fibrillarin transfected: sc-126852 (B) 293T whole cell lysates.
Fibrillarin (G-8): sc-374022. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar localization.
Fibrillarin (G-8): sc-374022. Immunoperoxidase staining of formalin fixed, paraffin-embedded human breast tissue showing nucleolar and nuclear staining of glandular cells.
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