CTGF Antibody (B-6): sc-373936
- CTGF Antibody (B-6) is a mouse monoclonal IgG3 κ, cited in 13 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 170-207 within an internal region of CTGF of human origin
- Anti-CTGF Antibody (B-6) is recommended for detection of CTGF of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and bovine
- Anti-CTGF Antibody (B-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG3 BP-HRP is the preferred secondary detection reagent for CTGF Antibody (B-6) for WB applications. This reagent is now offered in a bundle with CTGF Antibody (B-6) (see ordering information below).
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SEE ALSO...
CTGF Antibody (B-6) is a mouse monoclonal IgG3 kappa light chain antibody engineered to detect Connective Tissue Growth Factor (CTGF), also known as CCN2 or Hypertrophic Chondrocyte-Specific Gene Product 24 (Hcs24). anti-CTGF antibody (B-6) targets an epitope mapped to amino acids 170-207 within an internal region of human CTGF and is effective in recognizing CTGF from mouse, rat, human, equine, canine, and bovine species through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA) assays. CTGF is a pivotal member of the CCN family of immediate early proteins, characterized by its modular structure consisting of four conserved domains: IGFBP, VWC, TSP-1, and CT. This structural organization allows CTGF to interact with various receptors and extracellular matrix components, facilitating critical processes such as cell proliferation, migration, and extracellular matrix production, which are essential for tissue development, repair, and fibrosis. The cysteine-rich nature of CTGF enables the formation of disulfide bonds that stabilize its tertiary structure, enhancing its functionality in cellular signaling and matrix remodeling. CTGF is secreted by endothelial cells, fibroblasts, smooth muscle cells, and myofibroblasts, underscoring its significant role in vascular biology and the progression of fibrotic diseases. Elevated levels of CTGF are closely associated with numerous fibrotic conditions, including renal, hepatic, and pulmonary fibrosis, making CTGF a key target for research and therapeutic interventions aimed at mitigating fibrosis. The structural features of CTGF facilitate interaction with multiple growth factors and receptors, influencing cellular behavior and tissue architecture. Available in both non-conjugated and various conjugated forms such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® derivatives, CTGF (B-6) antibody provides versatile applications for diverse experimental needs.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CTGF Antibody (B-6) | sc-373936 | 200 µg/ml | $322.00 | |||
CTGF Antibody (B-6): m-IgG3 BP-HRP Bundle | sc-552961 | 200 µg Ab; 40 µg BP | $361.00 | |||
CTGF Antibody (B-6) AC | sc-373936 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CTGF Antibody (B-6) HRP | sc-373936 HRP | 200 µg/ml | $322.00 | |||
CTGF Antibody (B-6) FITC | sc-373936 FITC | 200 µg/ml | $336.00 | |||
CTGF Antibody (B-6) PE | sc-373936 PE | 200 µg/ml | $349.00 | |||
CTGF Antibody (B-6) Alexa Fluor® 488 | sc-373936 AF488 | 200 µg/ml | $364.00 | |||
CTGF Antibody (B-6) Alexa Fluor® 546 | sc-373936 AF546 | 200 µg/ml | $364.00 | |||
CTGF Antibody (B-6) Alexa Fluor® 594 | sc-373936 AF594 | 200 µg/ml | $364.00 | |||
CTGF Antibody (B-6) Alexa Fluor® 647 | sc-373936 AF647 | 200 µg/ml | $364.00 | |||
CTGF Antibody (B-6) Alexa Fluor® 680 | sc-373936 AF680 | 200 µg/ml | $364.00 | |||
CTGF Antibody (B-6) Alexa Fluor® 790 | sc-373936 AF790 | 200 µg/ml | $364.00 | |||
CTGF (B-6) Neutralizing Peptide | sc-373936 P | 100 µg/0.5 ml | $69.00 |