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Thyroglobulin Antibody (D-9): sc-365997

 |  Datasheet

(Based on data analysis)

  • Thyroglobulin Antibody (D-9) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 13-41 near the N-terminus of Thyroglobulin of human origin
  • recommended for detection of Thyroglobulin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
 

See additional Thyroglobulin Antibodies.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Thyroglobulin Antibody (D-9) sc-365997 200 µg/ml $279
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TG 7038 8q24.22 NM_003235 P01266
 608175
Mouse Tg 21819 15 D2 NM_009375 O08710
 N/A
 

Thyroglobulin is a large preprotein containing multiple glycosylation sites. Located in the thyroid gland, thyroglobulin is the precursor of the iodinated thyroid hormones thyroxine and triiodothyronine. Thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulum, prior to forming dimers. This dimerization, as well as export of thyroglobulin to the golgi complex, has been shown to require Ca2+. Defects in thyroglobulin are known to cause some types of goiter (an enlargement of the thyroid gland). This condition is thought to result from defective dimerization and transport of thyroglobulin to the golgi complex.
Thyroglobulin Antibody (D-9) Data
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sc-365997
Thyroglobulin (D-9): sc-365997. Western blot analysis of Thyroglobulin expression in rat thyroid tissue extract.
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