p-C3G Antibody (G-2) | Santa Cruz Biotech

Welcome to Santa Cruz Biotechnology!

Research Products
Primary Antibodies: Mammalian Phospho-Specific Antibodies Antibodies for IHC (Paraffin) Staining Flow Cytometry Veterinary Research Antibodies Primary Antibodies: Non-Mammalian siRNA and shRNA (plasmid and lentivirus) Products Protein A, G PLUS and L-Agarose Tissue Extracts and Cell Lysates Biologically Active and Purified Proteins Transfected Cell Lysates Secondary Antibodies, Control Antibodies and Normal Sera Specialty Reagents and Kits
Chemicals
Biochemicals Prepared Buffers Buffer Components and Standard Lab Chemicals Stains Dyes and Fluorescent Probes Solvents HRP and AP Substrates
Lab Supplies
Animal Health
Animal Health Promo Animal Health Book Promo Animal Health News Animal Health Pharmacy Ultra Cruz Supplements
What's New
Promotionals LIF Protein Veterinary Research Antibodies Monoclonal Antibodies New IHC (Paraffin) Staining
Information
Contact Us Order Information Cruz Credits™ Investigator Awards Job Opportunities Distributors
Support
Protocols Product Citations Datasheets / MSDS Technical Service Catalog Request Chromosome DBase

p-C3G Antibody (G-2): sc-365994	\| Datasheet

5 5 (Based on data analysis) 1

p-C3G Antibody (G-2) is a mouse monoclonal IgM provided at 200 µg/ml
specific for a short amino acid sequence containing phosphorylated Tyr 514 of C3G of mouse origin
recommended for detection of Tyr 514 phosphorylated C3G of mouse origin by WB, IP, IF and ELISA

See additional C3G Antibodies.

Ordering InformationGene Info

Recommended Support Products:

(click button of application of choice)

WB IP IF

Species	Gene Name	Gene ID	Chromosome Location	Isoform (mRNA) Accession #	Protein Accession #	OMIM™ Number

Mouse	Rapgef1	107746	2 B	NM_001039086, NM_001039087, NM_054050	NP_001034175	N/A

C3G (RAPGEF1, Rap guanine nucleotide exchange factor (GEF) 1, GRF2) is a human guanine nucleotide releasing protein for Ras protein. C3G belongs to the adaptor-type Src homology (SH2)-containing molecules. SH2 domains are globular protein modules present in a large variety of functionally distinct proteins. Src family kinases or pervanadate treatment induces phosphorylation of C3G on Tyrosine-504. C3G can interact with Hck and undergo tyrosine phosphorylation by treatment of human myelomonocytic THP-1 cells with mercuric chloride. C3G mRNA is ubiquitous in human adult and fetal tissues. C3G-dependent activation of Rap1 is required for adhesion and spreading of embryonic fibroblasts and for the early embryogenesis of the mouse. The human C3G gene encodes several transcript variants.

p-C3G Antibody (G-2) Data

Click on image to enlarge

Western blot analysis of C3G phosphorylation in untreated (A,C) and lambda protein phosphatase (sc-200312A) treated (B,D) K-562 whole cell lysates. Antibodies tested include p-C3G (G-2): sc-365994 (A,B) and C3G (H-300): sc-15359 (C,D).

Download

Datasheets

Get Adobe Acrobat Reader

p-C3G Antibody (G-2): sc-365994