Molecular structure of BMS-708163, CAS Number: 1146699-66-2
BMS-708163 (CAS 1146699-66-2)
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Alternate Names:
Avagacestat
Application:
BMS-708163 is a γ-secretase inhibitor
CAS Number:
1146699-66-2
Purity:
≥98%
Molecular Weight:
520.88
Molecular Formula:
C20H17ClF4N4O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
BMS-708163 is an inhibitor of the γ-secretase complex which is composed of four proteins: presenilin, nicastrin, APH-1 and PEN-2. BMS-708163 is shown to block Aβ40 and Aβ42 activity.
Inhibitor of:
Aph-1, Aph-1c, APLP1, C20orf78, EPHX2, fringe, Gamma-secretase, HES3, HES4, HES7, ITM2A, Jagged, KIAA1024L_A730017C20Rik, kismet-L, Manic Fringe, Notch, Nrarp, NUMB, PION, PSAP, RAM, SEL-12, SPPL3, TLE5, and X11α.Activator of:
1700016H13Rik, Aph-1b, C14orf135, DLN1, Dyrk2, HRT1_Hrt1, Lunatic Fringe, Notch 2, Radical Fringe, and SPPL3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BMS-708163, 10 mg | sc-364444 | 10 mg | $480.00 | |||
BMS-708163, 50 mg | sc-364444A | 50 mg | $1455.00 |