CruzFluor sm™ 2 succinimidyl ester

CruzFluor™ sm 2 (CFLsm2) family has the spectral properties similar to those of fluoresceins and Alexa Fluor® 488 (Alexa Fluor® is the trademark of Invitrogen). Compared to fluoresceins CFLsm2 family has much stronger fluorescence and higher photostability. Additionally their fluorescence is pH-independent from pH 3 to 11. These characteristics make this new dye family a superior alternative to fluoresceins. CFLsm2-labeled peptides and nucleotides exhibit much stronger fluorescence and higher photostability than the ones labeled with FITC or FAM. In pairing with our CruzQuench™ 2 (CQ2), a variety of FRET peptides and nucleotides can be developed for detecting proteases and molecular beacons with enhanced sensitivity and stability. In addition, CFLsm2 has spectral properties, pH dependence and photostability similar to Alexa Fluor® 488, making them excellent replacement to the expensive Alexa Fluor® 488.

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