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EDTA, disodium salt, dihydrate, for molecular biology (CAS 6381-92-6)

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Synonym:Edetate disodium salt dihydrate
Application:A chelating agent and inhibitor of metalloproteases
CAS Number:6381-92-6
Purity:≥99%
Grade:Molecular Biology
Molecular Weight:372.24
Molecular Formula:C10H14N2Na2O8·2H2O
Refer to Certificate of Analysis for lot specific data (including water content).
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Product NameCatalog #UnitPriceQtyAddFavorites
EDTA, disodium salt, dihydrate, for molecular biology sc-359904 50 g $26
EDTA, disodium salt, dihydrate, for molecular biology sc-359904A 250 g $79
Description
EDTA, disodium salt, dihydrate, for molecular biology is extensively used as a chelator of divalent cations such as Ca2+. EDTA (Ethylenediaminetetraacetic acid) is a chelating agent, a general chemical, and a sequestrant. In molecular biology applications, addition of EDTA minimizes the impact of metal ion contaminants. Also used to facilitate enzymatic reactions that could be inhibited by heavy metal traces. It also inhibits enzymes, such as metalloproteases, which require divalent cations for activity.
Technical Information
Appearance:Powder
Physical State:Solid
Solubility:Soluble in water (~100 g/l) at 20 °C, (95%) alcohol (Slightly soluble), and 3 M NaOH (100 mg/mL).
Storage:Store at room temperature
Melting Point:248 °C (lit.)(dec.)
Boiling Point:614.2 °C at 760 mmHg (Predicted)
Density:1.01 g/cm3 at 25 °C
Refractive Index:n20D 1.36
Safety and Reference Information
WGK Germany:2
RTECS:AH4410000
PubChem CID:636371
Merck Index:14: 3517
MDL Number:MFCD00150037
EC Number:205-358-3
Beilstein Registry:3900609
SMILES:C(CN(CC(=O)O)CC(=O)[O-])N(CC(=O)O)CC(=O)[O-].O.O.[Na+].[Na+]
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Van Kley, H. and Claywell, C.S. 1973. Clin. Chem. 19: 621-623. PMID: 4196140
2. Bhargava, K.K. and Acharya, S.A. 1989. Semin Nucl Med. 19: 187-201. PMID: 2503873
3. Brandt, K.D., et al. 1991. Bioconjug. Chem. 2: 67-70. PMID: 1908706
4. Jasin, H.E. and Taurog, J.D. 1991. J. Clin. Invest. 87: 1531-1536. PMID: 1708782
5. Lauer, S.A. and Nolan, J.P. 2002. Cytometry. 48: 136-145. PMID: 12116359
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