CD 3254 (CAS 196961-43-0)

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Synonym:	3-[4-Hydroxy-3-(5,6,7,8-tetrahtdro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid
Application:	A selective RXRα agonist
CAS Number:	196961-43-0
Purity:	≥97%
Molecular Weight:	364.48
Molecular Formula:	C₂₄H₂₈O₃

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
CD 3254	sc-358786	10 mg	$169
CD 3254	sc-358786A	50 mg	$712

Not available for sale outside of the United States.

Description

CD 3254 is a selective RXRα agonist which is reported to not exhibit activity at RARα, RARβ or RARγ receptors. RXRα belongs to the NR2B nuclear receptor family and primarily expressed in the liver, intestines, kidneys, and epidermis.

Technical Information

Appearance:	White
Physical State:	Solid
Solubility:	Soluble in ethanol (100 mM), and DMSO (100 mM).
Storage:	Store at -20° C
Refractive Index:	n²⁰_D 1.59 (Predicted)

Safety and Reference Information

PubChem CID:	44566110
SMILES:	CC1=CC2=C(C=C1C3=C(C=CC(=C3)/C=C/C(=O)O)O)C(CCC2(C)C)(C)C

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Pogenberg, V., et al. 2005. J. Biol. Chem. 280: 1625-1633. PMID: 15528208
2. Nahoum, V., et al. 2007. Proc .Natl. Acad. Sci. 104: 17323-17327. PMID: 17947383
3. le Maire, A., et al. 2009. EMBO. Rep. 10: 367-373. PMID: 19270714

SDS

Datasheet/SDS