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CD 3254 (CAS 196961-43-0)

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Synonym:3-[4-Hydroxy-3-(5,6,7,8-tetrahtdro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid
Application:A selective RXRα agonist
CAS Number:196961-43-0
Purity:≥97%
Molecular Weight:364.48
Molecular Formula:C24H28O3
Refer to Certificate of Analysis for lot specific data (including water content).
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Product NameCatalog #UnitPriceQtyAddFavorites
CD 3254 sc-358786 10 mg $179
CD 3254 sc-358786A 50 mg $739
Not available for sale outside of the United States.
Description
CD 3254 is a selective RXRα agonist which is reported to not exhibit activity at RARα, RARβ or RARγ receptors. RXRα belongs to the NR2B nuclear receptor family and primarily expressed in the liver, intestines, kidneys, and epidermis.
Technical Information
Physical State:Solid
Solubility:Soluble in ethanol (100 mM), and DMSO (100 mM).
Storage:Store at -20° C
Refractive Index:n20D 1.59 (Predicted)
Safety and Reference Information
PubChem CID:44566110
SMILES:CC1=CC2=C(C=C1C3=C(C=CC(=C3)/C=C/C(=O)O)O)C(CCC2(C)C)(C)C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Pogenberg, V., et al. 2005. J. Biol. Chem. 280: 1625-1633. PMID: 15528208
2. Nahoum, V., et al. 2007. Proc .Natl. Acad. Sci. 104: 17323-17327. PMID: 17947383
3. le Maire, A., et al. 2009. EMBO. Rep. 10: 367-373. PMID: 19270714
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Certificate of Analysis

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