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- Specifications
- Offered as 1 gram (sc-3520)
- CAS Number: 54-21-7
- Molecular Weight: 160.104
- Molecular Formula: C7H5O3•Na
- Purity: 99%
- SMILES: C1=CC=C(C(=C1)C(=O)[O-])O.[Na+]
- Description
- Sodium salicylate is a metabolite of acetylsalicylic acid (sc-217570), and functions by inhibiting NF-κB and reducing oxidative stress. The agent has the ability to protect against neurotoxicity induced by glutamate in rat studies. Along with aspirin (sc-202471), sodium salicylate is an anti-inflammatory compound that binds to and inhibits IKKβ (IKK-β). Sodium salicylate has been shown to reduce ATP binding in vitro and in vivo.
- Storage
- Store at room temperature
- Safety
- Risk Statements: R22,R36
- Safety Statements: S22,S24
- RTECS: VO5075000
- For Research Use Only
- Reference Numbers
- PubChem Compound ID: 16760658
- Merck Index: 14,8332
- MDL Number: MFCD00002440
- EC Number: 200-198-0
- Beilstein Registry Number: 3732792
- References
- 1. Kopp, E. and Ghosh, S. 1994. Science. 265: 956-959. PMID: 8052854
2. Grilli, M., et al. 1996. Science. 274: 1383-1385. PMID: 8910280
3. Yin, M.J., et al. 1998. Nature. 396: 77-80. PMID: 9817203
4. Fan, J.R., et al. 2010. Eur. J. Pharmacol. 638: 13-20. PMID: 20406630
5. He, B., et al. 2010. Hepatobiliary Pancreat Dis Int. 9: 49-53. PMID: 20133229
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Sodium Salicylate
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