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Ets-2 (C-20) Antibody: sc-351

 |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope mapping at the C-terminus of Ets-2 of human origin
  • recommended for detection of Ets-2 and, to a lesser extent, Ets-1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-351 X, 200 µg/0.1 ml
  • agarose conjugate for IP studies, sc-351 AC, 500 µg/0.25 ml agarose
  • blocking peptide, sc-351 P
 
Additional Ets Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ETS2 2114 21q22.2 NM_005239 P15036
164740
Mouse Ets2 23872 16 C4 P15037
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Ets-2 (C-20) sc-351 200 µg/ml $279
Ets-2 (C-20) AC sc-351 AC 500µg/ml, 25%ag $366
Ets-2 (C-20) P sc-351 P
(peptide)
100 µg/0.5 ml $61
Ets-2 (C-20) X sc-351 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Ets-2 siRNA (h) sc-37855 10 µM $258
Ets-2 siRNA (m) sc-37856 10 µM $258
Ets-2 (h)-PR sc-37855-PR 10 µM $23
Ets-2 (m)-PR sc-37856-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Ets-2 shRNA Plasmid (h) sc-37855-SH 20 µg $520
Ets-2 shRNA Plasmid (m) sc-37856-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Ets-2 shRNA (h) Lentiviral Particles sc-37855-V 200 µl $625
Ets-2 shRNA (m) Lentiviral Particles sc-37856-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Ets-2 (m): 293T Lysate sc-120131 100µg/200µl $205
Jurkat nuclear extract sc-2132 1000 µg $143
K-562 nuclear extract sc-2130 1000 µg $143
A-673 nuclear extract sc-2128 1000 µg $143
MCF7 nuclear extract sc-2149 1000 µg $143

Ets-2 Background Information
Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1–3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element. Evidence indicates that the DNA binding activity by Ets-1 is regulated at the level of phosphorylation.

Ets-2 (C-20) Product Citations
See how others have used Ets-2 (C-20): sc-351 antibody and or Ets-2 (C-20) antibody conjugates.


41 total citations
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Ets-2 (C-20)
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Ets-2 (C-20): sc-351. Western blot analysis of Ets-2 expression in HeLa (A), A-431 (B), MCF7 (C), A-673 (D), K-562 (E) and Jurkat (F,G) nuclear extracts.
Ets-2 (C-20): sc-351. Western blot analysis of Ets-2 expression in non-transfected: sc-117752 (A) and mouse Ets-2 transfected: sc-120131 (B) 293T whole cell lysates.
Ets-2 (C-20): sc-351. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and cytoplasmic localization.
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