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home » Tumor Suppressors/Apoptosis » EMSY Antibody / EMSY Antibodies » EMSY (A-15): sc-34995

EMSY (A-15) Antibody: sc-34995

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the N-terminus of EMSY of human origin
  • recommended for detection of EMSY isoforms 1 and 2 of mouse and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine, porcine and avian
  • blocking peptide, sc-34995 P
 
Additional EMSY Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human C11orf30 56946 11q13.5 NM_020193 Q7Z589
 608573
Mouse 2210018M11Rik 233545 7 E2 Q8BMB0
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
EMSY (A-15) sc-34995 200 µg/ml $279
EMSY (A-15) P sc-34995 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EMSY siRNA (h) sc-45565 10 µM $258
EMSY siRNA (m) sc-45566 10 µM $258
EMSY siRNA (h)-PR sc-45565-PR 10 µM $23
EMSY siRNA (m)-PR sc-45566-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EMSY shRNA Plasmid (h) sc-45565-SH 20 µg $520
EMSY shRNA Plasmid (m) sc-45566-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EMSY siRNA shRNA (h) Lentiviral Particles sc-45565-V 200 µl $625
EMSY siRNA shRNA (m) Lentiviral Particles sc-45566-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

EMSY Background Information
EMSY interacts with BRCA2 and plays a role in chromatin remodeling. This interaction has been confirmed in HeLa cells. Overexpression of EMSY strongly correlates with amplification in sporadic breast cancer and higher grade ovarian cancer. The EMSY gene is amplified in 18% of breast cancer cell lines. EMSY amplification is highly correlated with DNA amplification in both cell lines and primary tumors. This amplification is a general sign of poor prognosis and shortened disease-free survival time. EMSY from a wide variety of species has a conserved 80 amino acid sequence at the N-terminus. In irradiated MEFs (mouse embryonic fibroblasts), EMSY was found to migrate to damaged DNA.
EMSY (A-15)
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sc-34995
EMSY (A-15): sc-34995. Western blot analysis of EMSY expression in HeLa whole cell lysate.
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Datasheets
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