epitope mapping at the C-terminus of TudorSN of human origin
recommended for detection of TudorSN of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
blocking peptide, sc-34753 P
TransCruz reagent for Gel Supershift and ChIP applications, sc-34753 X, 200 µg/0.1 ml
TudorSN Background Information TudorSN functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. TudorSN also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. TudorSN plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
TudorSN (C-17)
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TudorSN (C-17): sc-34753. Western blot analysis of TudorSN expression in Jurkat (A), KNRK (B) and NIH/3T3 (C) nuclear extracts and rat (D) and mouse (E) liver tissue extracts.
TudorSN (C-17): sc-34753. Western blot analysis of TudorSN expression in non-transfected: sc-117752 (A) and mouse TudorSN transfected: sc-124365 (B) 293T whole cell lysates.