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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the C-terminus of TES of human origin
- recommended for detection of Testin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-34736 P
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Ordering Information
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TES Background Information
TES was originally identified as a candidate tumour suppressor gene and has been found to encode a novel focal adhesion protein called TES or Testin. TES localizes to cell-cell contacts, Actin stress fiber and interacts with a variety of cytoskeletal proteins including Zyxin, Mena, VASP, Talin and Actin. The ability of TES to associate with a-actinin, paxillin and Zyxin is dependent on the conformational state of the molecule. TES contains 3 LIM zinc-binding domains and may act as a tumor suppressor. Overexpression of the TES gene results in increased cell spreading and decreased cell motility.
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TES (D-18)
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TES (D-18): sc-34736. Western blot analysis of TES expression in non-transfected: sc-117752 (A) and mouse TES transfected: sc-123983 (B) 293T whole cell lysates. TES (D-18): sc-34736. Western blot analysis of TES expression in non-transfected: sc-117752 (A) and mouse TES transfected: sc-123982 (B) 293T whole cell lysates. |
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