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Stat1α p91 (C-24) Antibody: sc-345 |
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- rabbit polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of Stat1α p91 of human origin
- recommended for detection of Stat1α p91 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine and canine equine and canine
- blocking peptide, sc-345 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-345 X, 200 µg/0.1 ml
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Stat1α p91 Background Information
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-å and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3∫ appears to be activated by both while Stat3å is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and Myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
| Stat1α p91 (C-24) Product Citations |
See how others have used Stat1α p91 (C-24): sc-345 antibody and or Stat1α p91 (C-24) antibody conjugates.
43 total citations Loading citations.
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Stat1α p91 (C-24)
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Western blot analysis of Stat1a p91 and Stat1b p84 expression in nuclear extracts of phorbol ester-treated HeLa (A,D), A-431 (B,E) and K-562 (C,F) cells. Antibodies include Stat1a p91 (C-24): sc-345 (AC) and Stat1 p84/p91 (E-23): sc-346 (DF). Stat1α p91 (C-24): sc-345. Western blot analysis of Stat1α p91 If expression in HeLa whole cell lysate.
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