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OSCAR Antibody (S-16): sc-34233

 |  Datasheet

(Based on data analysis)
  • OSCAR Antibody (S-16) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of OSCAR of human origin
  • recommended for detection of OSCAR of human origin by WB, IF and ELISA
  • blocking peptide, sc-34233 P
 

See additional OSCAR Antibodies.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
OSCAR Antibody (S-16) sc-34233 200 µg/ml $279
OSCAR (S-16) P sc-34233 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
OSCAR siRNA (h) sc-45304 10 µM $258
OSCAR siRNA (h)-PR sc-45304-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
OSCAR shRNA Plasmid (h) sc-45304-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
OSCAR siRNA shRNA (h) Lentiviral Particles sc-45304-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human OSCAR 126014 19q13.42 NM_130771, NM_133168, NM_133169, NM_206817, NM_206818 Q8IYS5
 606862
 

Osteoclasts regulate homeostasis of bone development. Osteoclast-associated receptor (OSCAR) functions critically in osteoclast differentiation, and is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. The FcRgamma chain, a signal transducing adaptor molecule for Fc receptors, associates with OSCAR and is involved in the cell surface expression of OSCAR, which regulates differentiation. Human OSCAR is continually expressed during differentiation of CD14(+) monocytes into dendritic cells and after maturation.