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- goat polyclonal IgG, 200 µg/ml
- epitope mapping within RNA binding domain 1 near the N-terminus of SRp55 of human origin
- recommended for detection of SRp55 and, to a lesser extent, SRp40 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine, porcine and avian
- blocking peptide, sc-34197 P
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Ordering Information
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SRp55 Background Information
Pre-mRNA splicing is a critical step in the post-transcriptional regulation of gene expression. Several protein complexes are involved in proper mRNA splicing and transport. Serine/arginine-rich (SR) proteins SRp55, SRp30c, and htra2beta1 regulate exon 2 and 10 splicing. The first two inhibit both exons and SRp55 also plays a role in exon inclusion after the removal of intronic splicing silencer sequences. SRp55 plays a major role in maintaining normal FGFR1 alpha-exon inclusion. |
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SRp55 (D-14)
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SRp55 (D-14): sc-34197. Western blot analysis of SRp55 expression in CCRF-CEM (A), human PBL (B) and rat PBL (C) whole cell lysates and K-562 nuclear extract (D).
SRp55 (D-14): sc-34197. Western blot analysis of SRp55 expression in human PBL whole cell lysate.
SRp55 (D-14): sc-34197. Western blot analysis of SRp55 expression in PC-3 (A), K-562 (B), HL-60 (C) and CCRF-CEM (D) nuclear extracts.
SRp55 (D-14): sc-34197. Western blot analysis of SRp55 expression in human PBL (A), rat PBL (B) and mouse PBL (C) whole cell lysates and HeLa (D) and CCRF-CEM (E) nuclear extracts.
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