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- rabbit polyclonal IgG, 200µg/ml
- epitope corresponding to amino acids 173-332 mapping at the C-terminus of LDH-A of human origin
- recommended for detection of LDH-A, B, C and LDH-A-like 6A and 6B of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
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LDH Background Information
The lactate dehydrogenase family (LDH) catalyzes the final step of anaerobic glycolysis, the conversion of L-lactate and NAD to pyruvate and NADH. The LDH family consists of three members, LDH-A, LDH-B and LDH-C, all of which form tetramers consisting four subunits. However, each family member displays a specific tissue distribution pattern with LDH-A and LDH-B predominant in several tissues, specifically LDH-A in muscle and LDH-B in heart, while LDH-C expression is confined to the testis and sperm. LDHs function as powerful markers for germ cell tumors. The genes encoding human LDH-A and LDH-C map to chromosome 11, while the human LDH-B gene maps to chromosome 12. Deficiency in the LDH-A gene is linked to exertional myoglobinuria.
| LDH (H-160) Product Citations |
See how others have used LDH (H-160): sc-33781 antibody and or LDH (H-160) antibody conjugates.
4 total citations Loading citations.
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LDH (H-160)
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LDH (H-160): sc-33781. Western blot analysis of LDH expression in SK-N-SH (A), SJRH30 (B) and LADMAC (C) whole cell lysates.
LDH (H-160): sc-33781. Immuno?fluorescence staining of methanol-fixed HeLa cells showing cytoplasmic local?ization.
LDH (H-160): sc-33781. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes (low and high magnification). Kindly provided by The Swedish Human Protein Atlas (HPA) program.
LDH (H-160): sc-33781. Western blot analysis of LDH-C expression in non-transfected: sc-117752 (A) and human LDH-C transfected: sc-116878 (B) 293T whole cell lysates. LDH (H-160): sc-33781. Western blot analysis of LDH expression in 293T whole cell lysate (A) and mouse testis tissue extract (B).
LDH (H-160): sc-33781. Western blot analysis of LDH-A expression in non-transfected 293T: sc-117752 (A), mouse LDH-A transfected 293T: sc-127087 (B) and SK-N-SH (C) whole cell lysates. |
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