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ChemR23 Antibody (BZ332): sc-33726

 |  Datasheet

(Based on data analysis)
  • ChemR23 Antibody (BZ332) is a rat monoclonal IgG2a provided at 200 µg/ml
  • raised against an N-terminal peptide comprised of residues 8–32 of CMKLR1 of human origin
  • recommended for detection of ChemR23 of human origin by FCM
  • fluorescein (sc-33726 FITC), phycoerythrin (sc-33726 PE), PerCP (sc-33726 PerCP) and PerCP-Cy5.5 (sc-33726 PCPC5) conjugates for FCM, 100 tests
  • Alexa Fluor® 488 (sc-33726 AF488) and Alexa Fluor® 647 (sc-33726 AF647) conjugates for FCM or immunofluorescence; 100 µg/2 ml
 

See additional ChemR23 Antibodies.

Ordering InformationGene Info
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
ChemR23 Antibody (BZ332) sc-33726 200 µg/ml $279
ChemR23 Antibody (BZ332) Alexa Fluor® 488 sc-33726 AF488 100 µg/2 ml $314
ChemR23 Antibody (BZ332) Alexa Fluor® 647 sc-33726 AF647 100 µg/2 ml $314
ChemR23 Antibody (BZ332) FITC sc-33726 FITC 100 tests in 2 ml $292
ChemR23 Antibody (BZ332) PCPC5 sc-33726 PCPC5 100 tests in 2 ml $310
ChemR23 Antibody (BZ332) PE sc-33726 PE 100 tests in 2 ml $303
ChemR23 Antibody (BZ332) PerCP sc-33726 PerCP 100 tests in 2 ml $310
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ChemR23 siRNA (h) sc-44633 10 µM $258
ChemR23 (h)-PR sc-44633-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ChemR23 shRNA Plasmid (h) sc-44633-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ChemR23 shRNA (h) Lentiviral Particles sc-44633-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CMKLR1 1240 12q23.3 NM_004072 Q99788
 602351
 

The C-X3-C chemokine family is characterized by two cysteines separated by three amino acid residues. Fractalkine is a member of this chemokine family that binds CX3CR1, previously named V28, and chemokine b receptor-like 1 (CMKBRL1) with high affinity, to induce either leukocyte adhesion and migration or chemotactic functions. CX3CR1 functions with CD4 as a co-receptor for the HIV-1 virus envelope protein, and patients homozygous for a variant haplotype of CX3CR1 progress to AIDS more rapidly than those with other haplotypes. Chemokine receptor-like 1 (also designated G protein-coupled receptor DEZ or ChemR23) belongs to the G protein-coupled receptor 1 family. It is an integral membrane protein functioning as a receptor, possibly a chem-otactic peptide receptor. It also acts as a coreceptor for various SIV strains and for a primary HIV-1 strain. ChemR23 is highly expressed in developing osseous and cartilaginous tissue, brain, kidney, gastrointestinal tissues and myeloid tissue, as well as in adult parathyroid glands.
ChemR23 Antibody (BZ332) Data
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sc-33726
ChemR23 (BZ332) PE: sc-33726 PE. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal rat IgG2a: sc-2872.
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