COL7A1 Background Information The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.
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COL7A1 (4D2)
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COL7A1 (4D2): sc-33710. Immunofluorescence staining of normal human cornea frozen section showing basement membrane staining.
COL7A1 (4D2): sc-33710. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in glomeruli and tubules (low and high magnification). Kindly provided by The Swedish Human Protein Atlas (HPA) program.