rRNA (Y10b) Antibody: sc-33678

rRNA Background Information
Ribosomal RNA (rRNA) is a component of the ribosomes where amino acids are assembled into polypeptides to be made into proteins. rRNA molecules are very abundant and make up approximately 80% of the RNA molecules found in a typical eukaryotic cell. Eukaryotic ribosomes consist of four different rRNA molecules: 5S, 5.8S, 18S and 28S rRNA. 5.8S, 18S and 28S rRNA are synthesized in the nucleolus, while 5S rRNA is synthesized in the nucleus. All four combine with the ribosomal proteins in the nucleolus to form pre40S and pre60S ribosomal subunits. rRNA molecules play a major role in protein synthesis. Ribosomal RNA molecules are crucial in correctly positioning the mRNA and the peptidyl tRNA, they are involved in peptidyl transferase activity and they play a structural role by forming the scaffolding where ribosomal proteins assemble.