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AKAP 250 Antibody (M-300): sc-33578

 |  Datasheet

(Based on data analysis)

  • AKAP 250 Antibody (M-300) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1385-1684 mapping at the C-terminus of AKAP 250 of mouse origin
  • recommended for detection of AKAP 250 of mouse and rat origin by WB, IP, IF and ELISA
 

See additional AKAP Antibodies including AKAP 14, AKAP, AKAP 13, AKAP 149/121, AKAP 3, AKAP 7, AKAP 8L, AKAP 9, AKAP 10, AKAP 12, AKAP 79, AKAP 82, AKAP 95, AKAP 100, AKAP 121, AKAP 149, AKAP 150, AKAP 220, AKAP 2 and AKAP 250.

Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
AKAP 250 Antibody (M-300) sc-33578 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AKAP 250 siRNA (m) sc-44761 10 µM $258
AKAP 250 (m)-PR sc-44761-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AKAP 250 shRNA Plasmid (m) sc-44761-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AKAP 250 shRNA (m) Lentiviral Particles sc-44761-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Akap12 83397 10 A1 Q9WTQ5
 N/A
 

The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates (1). Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. This family of proteins has been designated A-kinase anchoring proteins (AKAP) (1-3). Members of this family, including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, and the DNA binding AKAP 95, display differential tissue specificity and localization (4-6). AKAP 250 (also designated gravin) interacts with ß2-adrenergic receptors to form dynamic complexes with protein kinases and phosphatases (7,8).

AKAP 250 Antibody (M-300) Data
Click on image to enlarge
sc-33578
AKAP 250 (M-300): sc-33578. Immunofluorescence staining of normal mouse intestine frozen section showing membrane and cytoplasmic staining.
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