Date published: 2025-10-26

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GP78 Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of GP78 monoclonal antibodies for advanced research in cellular biology. GP78 monoclonal antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GP78, also known as AMFR, is an E3 ubiquitin ligase that plays a central role in the endoplasmic reticulum-associated degradation (ERAD) pathway. The ERAD pathway maintains cellular homeostasis by regulating protein quality control. GP78 actively participates in the degradation of misfolded proteins, highlighting its significance in various physiological processes. Research has shown that GP78 may have important implications in diseases such as cancer and neurodegeneration. Understanding GP78's role in protein regulation and degradation can lead to significant breakthroughs in cellular function research. GP78 monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of cellular processes and disease mechanisms.

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GP78 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GP78 Antibody (3D9)

sc-293371mouse IgG2a κ451-550 (h)WB, IP, ELISAh
1
(1)

GP78-1 Antibody (F-3)

sc-166358mouse IgG1 κ87-116 (h)WB, IP, IF, ELISAm, r, h
11
(6)

GP78 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GP78 CRISPR/Cas9 KO Plasmid (h)

sc-402346hGene KnockoutGFP
1
(0)

GP78 HDR Plasmid (h)

sc-402346-HDRhHomology Directed RepairPuromycin
1
(0)

GP78 Double Nickase Plasmid (h)

sc-402346-NIChGene KnockoutPuromycin
1
(0)

GP78 Double Nickase Plasmid (h2)

sc-402346-NIC-2hGene KnockoutPuromycin
1
(0)

GP78 CRISPR/Cas9 KO Plasmid (m)

sc-423842mGene KnockoutGFP0
(0)

GP78 HDR Plasmid (m)

sc-423842-HDRmHomology Directed RepairPuromycin0
(0)

GP78 Double Nickase Plasmid (m)

sc-423842-NICmGene KnockoutPuromycin0
(0)

GP78 Double Nickase Plasmid (m2)

sc-423842-NIC-2mGene KnockoutPuromycin0
(0)

GP78 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GP78 CRISPR Activation Plasmid (h)

sc-402346-ACThGene ActivationPuro, Blast, Hygro
1
(0)

GP78 CRISPR Activation Plasmid (h2)

sc-402346-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

GP78 Lentiviral Activation Particles (h)

sc-402346-LAChGene ActivationPuro, Blast, Hygro
1
(0)

GP78 Lentiviral Activation Particles (h2)

sc-402346-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

GP78 CRISPR Activation Plasmid (m)

sc-423842-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GP78 CRISPR Activation Plasmid (m2)

sc-423842-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GP78 Lentiviral Activation Particles (m)

sc-423842-LACmGene ActivationPuro, Blast, Hygro0
(0)

GP78 Lentiviral Activation Particles (m2)

sc-423842-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GP78 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GP78 siRNA (h)

sc-43809hGene SilencingN/A
2
(0)

GP78 shRNA Plasmid (h)

sc-43809-SHhGene SilencingPuromycin
2
(0)

GP78 shRNA (h) Lentiviral Particles

sc-43809-VhGene SilencingPuromycin
2
(0)

GP78 siRNA (m)

sc-44579mGene SilencingN/A
1
(0)

GP78 shRNA Plasmid (m)

sc-44579-SHmGene SilencingPuromycin
1
(0)

GP78 shRNA (m) Lentiviral Particles

sc-44579-VmGene SilencingPuromycin
1
(0)