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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 21-80 mapping within an N-terminal extracellular domain of ETAR of mouse origin
- recommended for detection of ETAR of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
EDNRA |
1909 |
4q31.23 |
NM_001957 |
P25101
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157300 |
| Mouse |
Ednra |
13617 |
8 C1 |
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Q61614
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N/A |
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ETAR Background Information
Endothelin receptor A (ETAR), also known as EDNRA, ET1 Receptor, ETA, EDN1 and ET-AR is a member of the Guanine-binding regulatory protein-coupled receptor family. ETAR binds endothelins and has the highest affinity for its ligand ET1, as compared to the ETBR receptor. Both ET receptors, ETAR and ETBR, are activated by ET1, which results in inhibition of active lens sodium-potassium transport. Activation of the ET receptors also causes an increase in cytoplasmic calcium concentration in cultured lens epithelial cells. In addition, ETAR induces arachidonic acid accumulation. ETAR has seven hydrophobic transmembrane domains and is expressed in aorta, lung, atrium, kidney, placenta and prostate. Specifically, placental vascular smooth muscle cells (PVSMCs) exclusively express ETAR.
| ETAR (M-60) Product Citations |
See how others have used ETAR (M-60): sc-33536 antibody and or ETAR (M-60) antibody conjugates.
2 total citations Loading citations.
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ETAR (M-60)
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ETAR (M-60): sc-33536. Western blot analysis of ETAR expression in mouse lung tissue extract.
ETAR (M-60): sc-33536. Western blot analysis of ETAR expression in mouse heart (A) and mouse lung (B) tissue extracts.
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