epitope corresponding to phosphorylated Ser 427 of KID of human origin
recommended for detection of Serine 427 phosphorylated KID of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
KID Background Information Kinesin-like DNA binding protein (KID), also designated kinesin-like protein KIF22, is a member of the kinesin family and is involved in spindle formation. It can bind to microtubules and to DNA and is involved in the regulation of the movement of chromosomes along microtubules during mitosis. KID is a nuclear protein that colocalizes with mitotic chromosomes and the gene maps to chromosome 16p11.2. The gene encoding for KID, KNSL4, spans 16kb and consists of 13 introns and 14 exons. The N-terminal half of KID contains the kinesin-like motor domain, and there is a helix-hairpin-helix DNA binding domain at its C terminus. It has been reported that the subcellular localization of KID changes dramatically during cell division.
p-KID (Ser 427)
Click on image to enlarge
p-KID (Ser 427): sc-33400. Western blot analysis of KID phosphorylation in non-transfected: sc-117752 (A) and human KID transfected: sc-170134 (B) 293T whole cell lysates.
