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LEDGF/p75p52 (C-16) Antibody: sc-33371 |
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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of LEDGF of human origin
- recommended for detection of LEDGF of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and feline
- blocking peptide, sc-33371 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-33371 X, 200 µg/0.1 ml
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LEDGF/p75p52 Background Information The lens epithelium-derived growth factor (LEDGF), also designated p75p52, is a transcriptional coactivator that complexes with the human immunodeficiency virus type 1 (HIV-1) integrase. LEDGF/p75p52 is essential for the nuclear localization and chromosomal association of viral proteins. As the primary integrase-to-chromatin tethering factor for HIV-1, LEDGF/p75p52 is responsible for the cellular trafficking of lentiviral integrases. During apoptosis, LEDGF/p75p52 is cleaved at three sites by caspase-3 and caspase-7, contributing to the pathogenesis of atopic disorders.
| LEDGF/p75p52 (C-16) Product Citations |
See how others have used LEDGF/p75p52 (C-16): sc-33371 antibody and or LEDGF/p75p52 (C-16) antibody conjugates.
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LEDGF/p75p52 (C-16)
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LEDGF/p75p52 (C-16): sc-33371. Western blot analysis of LEDGF/p75p52 expression in non-transfected 293T: sc-117752 (A), human LEDGF/p75p52 transfected 293T: sc-117262 (B) and K-562 (C) whole cell lysates.
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