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p-ASK 1 Antibody (Ser 83): sc-33362

 |  Datasheet

(Based on data analysis)

  • p-ASK 1 Antibody (Ser 83) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to phosphorylated Ser 83 of ASK 1 of human origin
  • recommended for detection of Ser 83 phosphorylated ASK 1 of human origin by WB, IP, IF and ELISA
  • blocking peptide, sc-33362 P
 

See additional ASK 1 Antibodies.

Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-ASK 1 Antibody (Ser 83) sc-33362 200 µg/ml $279
p-ASK 1 (Ser 83) P sc-33362 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ASK 1 siRNA (h) sc-29748 10 µM $258
ASK 1 (h)-PR sc-29748-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ASK 1 shRNA Plasmid (h) sc-29748-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ASK 1 shRNA (h) Lentiviral Particles sc-29748-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
K-562 + TNFα Cell Lysate sc-24723 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MAP3K5 4217 6q23.3 NM_005923 Q99683
n/a
 


Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also called MAP kinase kinase kinases) phosphorylate and activate the MAP kinases, including ERK, JNK and p38. The MEK kinases characterized to date include Raf-1, Raf-B, MOS, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (also designated MEK kinase-5). MEK kinase-1 has been shown to phosphorylate MEK-1 via a Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK pathway. ASK 1 activates both MEK-4 and MEK-3/MEK-6 pathways. ASK 1 serine 83 is phosphorylated by Akt.

p-ASK 1 Antibody (Ser 83) Data
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p-ASK 1 (Ser 83): sc-33362. Western blot analysis of ASK 1 phosphorylation in non-transfected: sc-117752 (A) and human ASK 1 transfected: sc-111456 (B) 293T whole cell lysates.
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