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p-HMG-14 Antibody (Ser 6): sc-33359

 |  Datasheet

(Based on data analysis)
  • p-HMG-14 Antibody (Ser 6) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to phosphorylated Ser 6 of HMG-14 of mouse origin
  • recommended for detection of Ser 6 phosphorylated HMG-14 of mouse origin by WB, IF and ELISA
  • blocking peptide, sc-33359 P
 

See additional HMG Antibodies including HMG, HMG-1, HMG-1L1, HMG-I, HMG-Y, HMGI-C, HMG-2, HMG-3, HMG-4, HMG-14, HMG-17, HMG-20A and HMG-2L1.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-HMG-14 Antibody (Ser 6) sc-33359 200 µg/ml $279
p-HMG-14 (Ser 6) P sc-33359 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HMG-14 siRNA (m) sc-37987 10 µM $258
HMG-14 (m)-PR sc-37987-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HMG-14 shRNA Plasmid (m) sc-37987-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HMG-14 shRNA (m) Lentiviral Particles sc-37987-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Hmgn1 15312 16 C4 P18608
 N/A
 

The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription. HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates. HMG-14/17 proteins modify the nucleosomal organization of the 30 nmol chromatin fiber and mediate the unfolding of the higher order chromatin structure, thereby facilitating access to the underlying DNA sequence. Clustering of architectural elements, such as HMG proteins and linker histone subtypes into distinct domains, may lead to structural and functional heterogeneity along the chromatin fiber. In addition, HMG-14 and HMG-17 have been identified as constitutive components of mouse oocyte and embryonic chromatin that establish a link between the structure of embryonic chromatin and the normal progression of embryonic development. The phosphorylation of HMG-14 at Serine 6 may be be related to specific gene expression and present in growing, cycling cells.