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home » Membrane Receptors » ErbB Antibody / ErbB Antibodies » p-ErbB-4 (Tyr 1056): sc-33040

p-ErbB-4 (Tyr 1056) Antibody: sc-33040

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to phosphorylated Tyr 1056 of ErbB-4 of human origin
  • recommended for detection of Tyr 1056 phosphorylated ErbB-4 of r and h origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-33040 P
 
Additional ErbB Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ERBB4 2066 2q34 NM_005235 Q15303
 600543
Human ERBB4 2066 2q34 NM_001042599, NM_005235 NP_005226
 600543
Mouse Erbb4 13869 1 C3 Q61527
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
p-ErbB-4 (Tyr 1056) sc-33040 200 µg/ml $279
p-ErbB-4 (Tyr 1056) P sc-33040 P
(peptide)
 100 µg/0.5 ml $61
Lambda Phosphatase sc-200312 100,000 units $462
Lambda Phosphatase sc-200312A 20,000 units $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ErbB-4 siRNA (h) sc-35329 10 µM $258
ErbB-4 (h)-PR sc-35329-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ErbB-4 shRNA Plasmid (h) sc-35329-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ErbB-4 shRNA (h) Lentiviral Particles sc-35329-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
A-431 + EGF Whole Cell Lysate sc-2202 500 µg/200 µl $104

ErbB-4 Background Information
The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. The gene encoding ErbB-4 is expressed as a 1full length protein, which is proteolytically cleaved to produce a membrane-anchored cytoplasmic domain fragment and an ectodomain fragment. Phosphorylation of Tyr 1056 mediates the interaction of ErbB-4 with the Yes Associated Protein (YAP), which may regulate transcription. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum.

p-ErbB-4 (Tyr 1056) Product Citations
See how others have used p-ErbB-4 (Tyr 1056): sc-33040 antibody and or p-ErbB-4 (Tyr 1056) antibody conjugates.


2 total citations
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p-ErbB-4 (Tyr 1056)
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sc-33040
p-ErbB-4 (Tyr 1056): sc-33040. Western blot analysis of ErbB-4 phosphorylation in untreated (A) and EGF-treated (B) A-431 whole cell lysates.
sc-33040
p-ErbB-4 (Tyr 1056): sc-33040. Western blot analysis of ErbB-4 phosphorylation in untreated (A), EGF treated (B) and EGF treated and lambda protein phosphatase treated (C) A-431 whole cell lysates.
sc-33040
p-ErbB-4 (Tyr 1056): sc-33040. Western blot analysis of ErbB-4 phosphorylation in untreated (A), Neuregulin-1 treated (B) and Neuregulin-1 and lambda protein phosphatase (sc-200312A) treated (C) T-47D whole cell lysates.
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