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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the N-terminus of FBP2 of rat origin
- recommended for detection of FBP2 of h and r origin by WB, IP, IF and ELISA; also reactive with additional species, including porcine
- blocking peptide, sc-33031 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-33031 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
KHSRP |
8570 |
19p13.3 |
NM_003685 |
Q92945
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603445 |
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FBP2 Background Information
Activation of FUSE, the far-upstream element, is required for the proper ex-pression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein or Far upstream element binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxyl-terminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation.
| FBP2 (D-12) Product Citations |
See how others have used FBP2 (D-12): sc-33031 antibody and or FBP2 (D-12) antibody conjugates.
3 total citations Loading citations.
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FBP2 (D-12)
Click on image to enlarge
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FBP2 (D-12): sc-33031. Western blot analysis of FBP2 expression in non-transfected 293T: sc-117752 (A), mouse FBP2 transfected 293T: sc-178603 (B), HL-60 (C) and A-673 (D) whole cell lysates. |
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