epitope corresponding to amino acids 1-240 representing full length GSTT1 of human origin
recommended for detection of Glutathione S-transferase Theta 1 and 3 and, to a lesser extent, GSTT2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
GSTT Background Information The GST superfamily is made up of several subfamilies. Glutathione S-transferase P (GSTP1) belongs to the Pi subfamily and is involved in the conjugation of reduced glutathione to a variety of endogenous and exogenous hydrophobic electrophiles. Glutathione S-transferase Mu 1 (GSTM1) is a cytoplasmic liver protein belonging to the Mu family and has the same basic functions as GSTP1-1. Glutathione S-transferase theta 1 (GSTT1) is a cytoplasmic homodimer expressed in erythrocytes. It belongs to the Theta family. Aside from being active in the reduced glutathione conjugation, this protein displays glutathione peroxidase activity with cumene hydroperoxide.
GSTT (FL-240)
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GSTT (FL-240): sc-32938. Western blot analysis of mouse liver tissue extract.
GSTT (FL-240): sc-32938. Western blot analysis of GSTT1 expression in non-transfected: sc-117752 (A) and mouse GSTT1 transfected: sc-120670 (B) 293T whole cell lysates.
