Date published: 2025-10-26

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MAT Antibodies

Santa Cruz Biotechnology features a diverse variety of MAT Antibodies for the detection and analysis of methionine adenosyltransferase (MAT). MAT Antibodies are validated for multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Methionine adenosyltransferase plays a crucial role in the synthesis of S-adenosylmethionine (SAM), a key methyl donor involved in numerous biological processes, including methylation reactions and the regulation of gene expression. The proper functioning of MAT is essential for cellular metabolism and the maintenance of cellular homeostasis, making it a significant target for research in various fields, including cancer and metabolic disorders. MAT research has revealed important insights into cellular methylation pathways and their impact on gene regulation. Understanding MAT function continues to expand knowledge about fundamental cellular processes and disease mechanisms. Recent studies have highlighted the importance of MAT in developmental biology and cellular differentiation. Santa Cruz Biotechnology monoclonal antibodies for MAT support researchers worldwide in advancing scientific understanding of cellular metabolism and disease mechanisms.

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MAT Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MAT Iα/IIα Antibody (B-10)

sc-166452mouse IgG2b κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
6
(4)

MAT Iα/IIα Antibody (A-10)

sc-166183mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

MAT II Antibody (F-12)

sc-398917mouse IgG2a κ69-92 (h)WB, IP, IF, ELISAm, r, h

new

(1)

MAT IIβ Antibody (A-3)

sc-390586mouse IgG2b κ32-51 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(2)

MAT IIβ Antibody (G-6)

sc-514068mouse IgG2a κ35-334 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

MAT IIβ Antibody (H-4)

sc-514069mouse IgG1 κ35-334 (h)WB, IP, IF, ELISAm, r, h

new

(2)

MAT CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MAT Iα CRISPR/Cas9 KO Plasmid (h)

sc-405476hGene KnockoutGFP0
(0)

MAT Iα HDR Plasmid (h)

sc-405476-HDRhHomology Directed RepairPuromycin0
(0)

MAT Iα Double Nickase Plasmid (h)

sc-405476-NIChGene KnockoutPuromycin0
(0)

MAT Iα Double Nickase Plasmid (h2)

sc-405476-NIC-2hGene KnockoutPuromycin0
(0)

MAT Iα CRISPR/Cas9 KO Plasmid (m)

sc-419102mGene KnockoutGFP0
(0)

MAT Iα CRISPR/Cas9 KO Plasmid (m2)

sc-419102-KO-2mGene KnockoutGFP0
(0)

MAT Iα HDR Plasmid (m2)

sc-419102-HDR-2mHomology Directed RepairPuromycin0
(0)

MAT Iα Double Nickase Plasmid (m)

sc-419102-NICmGene KnockoutPuromycin0
(0)

MAT Iα Double Nickase Plasmid (m2)

sc-419102-NIC-2mGene KnockoutPuromycin0
(0)

MAT IIα CRISPR/Cas9 KO Plasmid (h)

sc-402566hGene KnockoutGFP0
(0)

MAT IIα HDR Plasmid (h)

sc-402566-HDRhHomology Directed RepairPuromycin0
(0)

MAT IIα Double Nickase Plasmid (h)

sc-402566-NIChGene KnockoutPuromycin0
(0)

MAT IIα Double Nickase Plasmid (h2)

sc-402566-NIC-2hGene KnockoutPuromycin0
(0)

MAT IIα CRISPR/Cas9 KO Plasmid (m)

sc-433137mGene KnockoutGFP0
(0)

MAT IIα HDR Plasmid (m)

sc-433137-HDRmHomology Directed RepairPuromycin0
(0)

MAT IIα Double Nickase Plasmid (m)

sc-433137-NICmGene KnockoutPuromycin0
(0)

MAT IIα Double Nickase Plasmid (m2)

sc-433137-NIC-2mGene KnockoutPuromycin0
(0)

MAT IIβ CRISPR/Cas9 KO Plasmid (h)

sc-404614hGene KnockoutGFP0
(0)

MAT IIβ HDR Plasmid (h)

sc-404614-HDRhHomology Directed RepairPuromycin0
(0)

MAT IIβ Double Nickase Plasmid (h)

sc-404614-NIChGene KnockoutPuromycin0
(0)

MAT IIβ Double Nickase Plasmid (h2)

sc-404614-NIC-2hGene KnockoutPuromycin0
(0)

MAT IIβ CRISPR/Cas9 KO Plasmid (m)

sc-430833mGene KnockoutGFP0
(0)

MAT IIβ HDR Plasmid (m)

sc-430833-HDRmHomology Directed RepairPuromycin0
(0)

MAT IIβ Double Nickase Plasmid (m)

sc-430833-NICmGene KnockoutPuromycin0
(0)

MAT IIβ Double Nickase Plasmid (m2)

sc-430833-NIC-2mGene KnockoutPuromycin0
(0)

MAT CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MAT Iα CRISPR Activation Plasmid (h)

sc-405476-ACThGene ActivationPuro, Blast, Hygro0
(0)

MAT Iα CRISPR Activation Plasmid (h2)

sc-405476-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MAT Iα Lentiviral Activation Particles (h)

sc-405476-LAChGene ActivationPuro, Blast, Hygro0
(0)

MAT Iα Lentiviral Activation Particles (h2)

sc-405476-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MAT Iα CRISPR Activation Plasmid (m)

sc-419102-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MAT Iα CRISPR Activation Plasmid (m2)

sc-419102-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MAT Iα Lentiviral Activation Particles (m)

sc-419102-LACmGene ActivationPuro, Blast, Hygro0
(0)

MAT Iα Lentiviral Activation Particles (m2)

sc-419102-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MAT IIα CRISPR Activation Plasmid (h)

sc-402566-ACThGene ActivationPuro, Blast, Hygro0
(0)

MAT IIα CRISPR Activation Plasmid (h2)

sc-402566-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MAT IIα Lentiviral Activation Particles (h)

sc-402566-LAChGene ActivationPuro, Blast, Hygro0
(0)

MAT IIα Lentiviral Activation Particles (h2)

sc-402566-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MAT IIα CRISPR Activation Plasmid (m)

sc-433137-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MAT IIα CRISPR Activation Plasmid (m2)

sc-433137-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MAT IIα Lentiviral Activation Particles (m)

sc-433137-LACmGene ActivationPuro, Blast, Hygro0
(0)

MAT IIα Lentiviral Activation Particles (m2)

sc-433137-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MAT IIβ CRISPR Activation Plasmid (h)

sc-404614-ACThGene ActivationPuro, Blast, Hygro0
(0)

MAT IIβ CRISPR Activation Plasmid (h2)

sc-404614-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MAT IIβ Lentiviral Activation Particles (h)

sc-404614-LAChGene ActivationPuro, Blast, Hygro0
(0)

MAT IIβ Lentiviral Activation Particles (h2)

sc-404614-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

MAT IIβ CRISPR Activation Plasmid (m)

sc-430833-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MAT IIβ Lentiviral Activation Particles (m)

sc-430833-LACmGene ActivationPuro, Blast, Hygro0
(0)

MAT IIβ Lentiviral Activation Particles (m2)

sc-430833-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MAT siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MAT Iα siRNA (h)

sc-106202hGene SilencingN/A
1
(0)

MAT Iα shRNA Plasmid (h)

sc-106202-SHhGene SilencingPuromycin
1
(0)

MAT Iα shRNA (h) Lentiviral Particles

sc-106202-VhGene SilencingPuromycin
1
(0)

MAT Iα siRNA (m)

sc-149291mGene SilencingN/A0
(0)

MAT Iα shRNA Plasmid (m)

sc-149291-SHmGene SilencingPuromycin0
(0)

MAT Iα shRNA (m) Lentiviral Particles

sc-149291-VmGene SilencingPuromycin0
(0)

MAT IIα siRNA (h)

sc-106203hGene SilencingN/A
1
(0)

MAT IIα shRNA Plasmid (h)

sc-106203-SHhGene SilencingPuromycin
1
(0)

MAT IIα shRNA (h) Lentiviral Particles

sc-106203-VhGene SilencingPuromycin
1
(0)

MAT IIα siRNA (m)

sc-149292mGene SilencingN/A
1
(0)

MAT IIα shRNA Plasmid (m)

sc-149292-SHmGene SilencingPuromycin
1
(0)

MAT IIα shRNA (m) Lentiviral Particles

sc-149292-VmGene SilencingPuromycin
1
(0)

MAT IIβ siRNA (h)

sc-75753hGene SilencingN/A0
(0)

MAT IIβ shRNA Plasmid (h)

sc-75753-SHhGene SilencingPuromycin0
(0)

MAT IIβ shRNA (h) Lentiviral Particles

sc-75753-VhGene SilencingPuromycin0
(0)

MAT IIβ siRNA (m)

sc-75754mGene SilencingN/A0
(0)

MAT IIβ shRNA Plasmid (m)

sc-75754-SHmGene SilencingPuromycin0
(0)

MAT IIβ shRNA (m) Lentiviral Particles

sc-75754-VmGene SilencingPuromycin0
(0)