epitope corresponding to amino acids 761-900 mapping near the C-terminus of MRTF-A of human origin
recommended for detection of Myocardin-related transcription factor A of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
MRTF-A Background Information Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factor A (MRTF-A) interacts with SRF and stimulates its transcriptional activity.
MRTF-A (H-140) Product Citations
See how others have used MRTF-A (H-140): sc-32909 antibody and or MRTF-A (H-140) antibody conjugates.
