epitope corresponding to amino acids 71-370 mapping within an internal region of PAK6 of human origin
recommended for detection of PAK6 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine and bovine
PAK6 Background Information The p21(CDKN1A)-activated kinases (PAKs) are serine/threonine protein kinases that bind to activated small GTPases, including Cdc42 and Rac, and influence transcription, cell morphology (cytoskeleton rearrangement), motility, and apoptosis. PAK family members contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK6 protein cotranslocates into the nucleus with androgen receptor, which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development, in response to androgen. PAK6 transcripts are present at high levels in brain and testis, with lower levels in multiple tissues including prostate and breast. The human PAK6 gene maps to chromosome 15q14.
PAK6 (H-300)
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PAK6 (H-300): sc-32857. Western blot analysis of PAK6 expression in non-transfected: sc-117752 (A) and human PAK6 transfected: sc-115034 (B) 293T whole cell lysates.
PAK6 (H-300): sc-32857. Western blot analysis of PAK6 expression in non-transfected: sc-117752 (A) and human PAK6 transfected: sc-158808 (B) 293T whole cell lysates.
PAK6 (H-300): sc-32857. Western blot analysis of PAK6 expression in SK-N-MC whole cell lysate.
AK6 (H-300): sc-32857. Immunofluorescence staining of methanol-fixed untransfected (A) and human PAK6 transfected HEK 293T cells (B).
