mapping the globular (G) carboxyterminal domain of the α-3 subunit of Laminin-5
recommended for detection of α-3 subunit of Laminin-5, 6 and 7 of rat origin by WB, IP, IF and IHC(P); non cross-reactive with human or mouse α-3 chain
also provided azide-free for prevents adhesion to rat α-3 subunit, sc-32794 L, 200 µg/0.1 ml
Laminin-5 Background Information Laminin-5 is a glycoprotein complex of three subunits (laminin -alpha3, -beta3, and -gamma2) that influences cell adhesion (metastasis), signal transduction and keratinocyte differentiation. Laminin-5 localizes to the basal lamina underneath epithelia and mediates the anchoring of basal epithelial cells to the extracellular matrix (ECM). Differential processing of the subunits of the Laminin-5 precursor influences how this protein integrates into the ECM architecture.
