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galectin-3 Antibody (B2C10): sc-32790

 |  Datasheet

(Based on data analysis)

  • galectin-3 Antibody (B2C10) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against recombinant galectin-3 of human origin with an epitope mapping within the first 18 amino acids
  • recommended for detection of galectin-3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
  • also provided azide-free for neutralizing, sc-32790 L, 200 µg/0.1 ml
  • fluorescein (sc-32790 FITC) and phycoerythrin (sc-32790 PE) conjugate for FCM, 100 tests
  • See 8 citations for galectin-3 Antibody (B2C10)
 

See additional galectin Antibodies including galectin, galectin-1, galectin-16, galectin-2, galectin-3, galectin-4, galectin-5, galectin-6, galectin-7, galectin-8, galectin-9, galectin-10, galectin-12, galectin-13 and galectin-14.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   FCM   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
galectin-3 Antibody (B2C10) sc-32790 200 µg/ml $279
Galectin-3 Antibody (B2C10) FITC sc-32790 FITC 100 tests in 2 ml $292
galectin-3 Antibody (B2C10) L sc-32790 L 200 µg/0.1 ml $279
Galectin-3 Antibody (B2C10) PE sc-32790 PE 100 tests in 2 ml $303
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
galectin-3 siRNA (h) sc-155994 10 µM $258
galectin-3 siRNA (m) sc-35443 10 µM $258
galectin-3 (h)-PR sc-155994-PR 10 µM, 20 µl $23
galectin-3 (m)-PR sc-35443-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
galectin-3 shRNA Plasmid (h) sc-155994-SH 20 µg $520
galectin-3 shRNA Plasmid (m) sc-35443-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
galectin-3 shRNA (h) Lentiviral Particles sc-155994-V 200 µl $625
galectin-3 shRNA (m) Lentiviral Particles sc-35443-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MCF7 nuclear extract sc-2149 250 µg/0.05 ml $143
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
SW480 Cell Lysate sc-2219 500 µg/200 µl $104
RAW 264.7 Whole Cell Lysate sc-2211 500 µg/200 µl $104
galectin-3 (h2): 293T Lysate sc-176286 100 µg/200 µl $205
galectin-3 (h): 293T Lysate sc-116566 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human LGALS3 3958 14q22.3 NM_002306, NM_194327 P17931
153619
Mouse Lgals3 16854 14 C1 P16110
N/A
 


Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) inter- actions and play a role in tumor progression, pre-mRNA splicing and apop-tosis. The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. Galectin-3 mediates the endocytosis of ∫1 Integrins in a lactose-dependent manner and is associated with thyroid malignancy and Crohn’s disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.

galectin-3 Antibody (B2C10) Product Citations
See how others have used galectin-3 Antibody (B2C10) and or galectin-3 Antibody (B2C10) conjugates.


8 total citations
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galectin-3 Antibody (B2C10) Data
Click on image to enlarge
galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in HeLa (A) and SW480 (B) nuclear extracts and A-431 (C) and T84 (D) whole cell lysates.
galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in non-transfected 293T: sc-117752 (A), human galectin-3 transfected 293T: sc-116566 (B) and HeLa (C) whole cell lysates.
galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in T84 whole cell lysate.
galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in A-431 (A) and T84 (B) whole cell lysates.
galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in non-transfected: sc-117752 (A) and human galectin-3 transfected: sc-176286 (B) 293T whole cell lysates.
galectin-3 (B2C10): sc-32790. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic staining of glandular cells.
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