galectin-3 (B2C10) Antibody sc-32790

santa cruz biotechnology, inc.

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galectin-3 (B2C10) Antibody: sc-32790	\| Datasheet

mouse monoclonal IgG₁; 200 µg/ml
raised against recombinant galectin-3 of human origin with an epitope mapping within the first 18 amino acids
recommended for detection of galectin-3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
also provided azide-free for neutralizing, sc-32790 L, 200 µg/0.1 ml
fluorescein (sc-32790 FITC) and phycoerythrin (sc-32790 PE) conjugate for FCM, 100 tests

Additional galectin Antibodies ...

Ordering InformationProduct Citations

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WB IP IF IHC(P) FCM siRNA

Species	Gene Name	Gene ID	Chromosome Location	Isoform (mRNA) Accession #	Protein Accession #	OMIM™ Number

Human	LGALS3	3958	14q22.3	NM_002306, NM_194327	P17931	153619
Mouse	Lgals3	16854	14 C1		P16110	N/A

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Ordering Information

Product Name	Catalog #	Unit	Price
galectin-3 (B2C10)	sc-32790	200 µg/ml	$279
Galectin-3 (B2C10) FITC	sc-32790 FITC	100 tests in 2 ml	$292
galectin-3 (B2C10) L	sc-32790 L	200 µg/0.1 ml	$279
Galectin-3 (B2C10) PE	sc-32790 PE	100 tests in 2ml	$303

siRNA Gene Silencers (click product name for more information)

Product Name	Catalog #	Unit	Price
galectin-3 siRNA (h)	sc-155994	10 µM	$258
galectin-3 siRNA (m)	sc-35443	10 µM	$258
galectin-3 (h)-PR	sc-155994-PR	10 µM, 20 µl	$23
galectin-3 (m)-PR	sc-35443-PR	10 µM	$23

shRNA Plasmids (click product name for more information)

Product Name	Catalog #	Unit	Price	Qty	Add	Favorites
galectin-3 shRNA Plasmid (h)	sc-155994-SH	20 µg	$520
galectin-3 shRNA Plasmid (m)	sc-35443-SH	20 µg	$520

shRNA Lentiviral Particles (click product name for more information)

Product Name	Catalog #	Unit	Price	Qty	Add	Favorites
galectin-3 shRNA (h) Lentiviral Particles	sc-155994-V	200 µl	$625
galectin-3 shRNA (m) Lentiviral Particles	sc-35443-V	200 µl	$625

WB Positive Control Cell Lysates (click product name for more information)

Product Name	Catalog #	Unit	Price
MCF7 nuclear extract	sc-2149	1000 µg	$143
HeLa Whole Cell Lysate	sc-2200	500 µg/200 µl	$104
A-431 Whole Cell Lysate	sc-2201	500 µg/200 µl	$104
SW480 Cell Lysate	sc-2219	500 µg/200 µl	$104
RAW 264.7 Whole Cell Lysate	sc-2211	500 µg/200 µl	$104
galectin-3 (h2): 293T Lysate	sc-176286	100µg/200µl	$205
galectin-3 (h): 293T Lysate	sc-116566	100µg/200µl	$205

galectin-3 Background Information
Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) inter- actions and play a role in tumor progression, pre-mRNA splicing and apop-tosis. The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. Galectin-3 mediates the endocytosis of ∫1 Integrins in a lactose-dependent manner and is associated with thyroid malignancy and Crohn’s disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.

galectin-3 (B2C10) Product Citations

See how others have used galectin-3 (B2C10): sc-32790 antibody and or galectin-3 (B2C10) antibody conjugates.

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galectin-3 (B2C10)

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galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in HeLa (A) and SW480 (B) nuclear extracts and A-431 (C) and T84 (D) whole cell lysates.

galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in non-transfected 293T: sc-117752 (A), human galectin-3 transfected 293T: sc-116566 (B) and HeLa (C) whole cell lysates.

galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in T84 whole cell lysate.

galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in A-431 (A) and T84 (B) whole cell lysates.

galectin-3 (B2C10): sc-32790. Western blot analysis of galectin-3 expression in non-transfected: sc-117752 (A) and human galectin-3 transfected: sc-176286 (B) 293T whole cell lysates.

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galectin-3 (B2C10) Antibody: sc-32790