 |
- mouse monoclonal IgG1; 200 µg/ml
- raised against mouse B cell lymphoma L1.2 transfectants expressing BAFF-R of human origin
- recommended for detection of BAFF-R of human origin by IF, IHC(P) and FCM
- fluorescein (sc-32774 FITC) and phyco-erythrin (sc-32774 PE) conjugates for FCM, 100 tests
- also provided azide-free for neutraliza-tion studies, sc-32774 L, 200 µg/0.1 ml
|
|
| |
Ordering Information
Recommended Support Products:
(click button of application of choice)
| |
| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
TNFRSF13C |
115650 |
22q13.2 |
NM_052945 |
Q96RJ3
|
606269 |
| |
BAFF-R Background Information
TNF cytokine family member TALL-1 (also designated BAFF, zTNF4, THANK and BLYS) is a type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. TALL-1 has the ability to bind to three receptors, TACI, BCMA and BAFF-R, but unlike other TNF receptors, BAFF-R specifically binds only the TALL-1 ligand. The gene encoding human BAFF-R, which maps to chromosome 22q13.1-q13.31, is expressed at high levels in spleen and lymph nodes and at lower levels in peripheral blood leukocytes and thymus. Expression of BAFF-R is crucial for selecting transitional B cells into the mature B cell pool. |
|
|
BAFF-R (11C1)
Click on image to enlarge
|
BAFF-R (11C1): sc-32774. Indirect FCM analysis of human peripheral blood leukocytes stained with BAFF-R (11C1), followed by PE-conjugated goat anti-mouse IgG1: sc-3764. Quadrant markers were set based on the isotype control, normal mouse IgG1: sc-3877. BAFF-R (11C1): sc-32774. Immunofluorescence staining of methanol-fixed TE671 cells showing cytoskeletal localization.
BAFF-R (11C1): sc-32774. Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing membrane staining of B cell follicles.
BAFF-R (11C1): sc-32774. Immunofluorescence staining of methanol-fixed TE671 cells showing cytoskeletal localization.
|
|
Download
|
|
