santa cruz biotechnology, inc.
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- mouse monoclonal IgG1; 200 µg/ml
- raised against recombinant MCP-1 of human origin
- recommended for detection of MCP-1 of human origin by WB, IP and IF
- also provided azide-free for neutralizing, sc-32771 L, 200 µg/0.1 ml
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Ordering Information
Recommended Support Products:
(click button of application of choice)
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
CCL2 |
6347 |
17q12 |
NM_002982 |
P13500
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609423 |
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MCP-1 Background Information
Eotaxin and the monocyte chemotactic proteins, MCP-1–5, form a subfamily of the C-C (or ∫) chemokines, which are characterized by a set of conserved adjacent cysteines. MCPs are produced by a variety of cells, including T lymphocytes, subsequent to their activation with cytokines such as IL-1, TNFå and IFN-©. In vitro studies have shown that the MCP isoforms exhibit their chemotactic effects on different subpopulations of lymphocytes. MCP-1 is a potent basophil activator but does not affect eosinophils. MCP-1 levels are increased during infection and inflammation, which are both characterized by leukocyte infiltration. Two MCP-1 receptors, which differ in their carboxy-termini, have been identified. |
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MCP-1 (5J)
Click on image to enlarge
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MCP-1 (5J): sc-32771. Western blot analysis of human recombinant MCP-1.
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